ArticleNutrients2022
Smoking Exposure Is Associated with Serum Vitamin D Deficiency in Children: Evidence from the Japan Environment and Children's Study.
Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Effect of smoking on vitamin D status in the adults of Henan, China: the role of HDL-C and LDL-C.Scientific reports · 2026Article
- Evaluating knowledge, awareness, attitudes, and practices regarding vitamin D in pregnant and postnatal Ghanaian women: a cross-sectional study.BMC public health · 2025Article
- Supplementation Behavior and Expenditures in Healthy German Vegans, Lacto-Ovo-Vegetarians and Omnivores: A Cross-Sectional Study.American journal of lifestyle medicine · 2025Article
- The joint effect of vitamin-D status and tobacco exposure on overweight and obesity in children.The British journal of nutrition · 2024Article
- Vitamin D Status in an Italian Pediatric Cohort: Is There a Role for Tobacco Smoking Exposure?Journal of clinical research in pediatric endocrinology · 2024Article
- The Association Between Serum 25-hydroxyvitamin D and Glycemic Control in Patients With Diabetes Mellitus: A Single-Center Retrospective Study.Journal of the ASEAN Federation of Endocrine Societies · 2023Article
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
Tobacco smoke exposure is known to lower serum 25-hydroxyvitamin D (25(OH)D) concentrations. This study evaluated the association between passive smoking and vitamin D deficiency (VDD) in young children using data from the Japan Environment and Children's Study (JECS), the largest birth cohort study in Japan. Information on parental smoking status was extracted from a survey of JECS for children aged 1.5 years and data for serum 25(OH)D concentrations were obtained from blood tests in the Sub-Cohort Study of JECS performed at age 2 years. Logistic regression and linear models were fitted to evaluate the association between these variables. Data were analyzed for 4593 children. After adjusting for covariates, smoke exposure was significantly associated with increased incidence of VDD (OR 1.35; 95% CI, 1.14-1.59) according to the logistic model. The linear model indicated that passive smoking negatively predicted de-seasonalized serum 25(OH)D concentrations (β -0.5; 95% CI -0.95 to -0.08) in children aged 2 years. The results suggest that smoke exposure is a risk factor for VDD in children. Given that VD plays a crucial role in bone metabolism and the immune system, our findings are significant for clinical and public health.
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