ArticleJournal of clinical medicine2022
Lip Lifting Efficacy of Hyaluronic Acid Filler Injections: A Quantitative Assessment Using 3-Dimensional Photography.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Different Techniques and Quantitative Measurements in Upper lip lift: A Systematic Review.Aesthetic plastic surgery · 2023Pooled it
- Defining and measuring 'Lift' in soft tissue filler-based facial rejuvenation: a critical review and proposed framework.JPRAS open · 2026Article
- Three-Dimensional Morphometric Trajectories Following Lip Lift With or Without Fat Grafting in Facial Feminization Patients.Aesthetic surgery journal. Open forum · 2026Article
- Prospective assessment on the cephalometric profile changes induced by labial hyaluronic acid infiltrations: A before-and-after study.Journal of clinical and experimental dentistry · 2026Review
- Hyaluronic Acid Injection Techniques for Lip Augmentation-Comparison of Linear, Retrograde, and Microdeposit Approaches: A Systematic Review.Aesthetic surgery journal. Open forum · 2026Review
- Interobserver reliability in the 3D facial scan assessment of the outcome in dermal filler therapy.Head & face medicine · 2025Article
- AI-Driven Assessment of Lip Volume Improvement Using Hyaluronic Acid Fillers: A Comprehensive Analysis.Aesthetic plastic surgery · 2025Article
- Anatomical-Based Diagnosis and Filler Injection Techniques: Lips and Philtrum.Life (Basel, Switzerland) · 2025Review
- The Tri-Lift suspension technique: a modified deep-plane lip lift for enhanced aesthetic outcomes-my personal approach.Maxillofacial plastic and reconstructive surgery · 2025Article
- Combination of Hyaluronic Acid and Polynucleotides Injection for the Treatment of Cheilitis Simplex.Clinical, cosmetic and investigational dermatology · 2025Article
- Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The study aimed to compare the volume enhancement and the lifting capacity of two different hyaluronic acid gels for lip injection. Thirty-six Korean female patients were randomized into two groups according to the cross-linking degree of the hyaluronic acid filler injected. Using a fixed injection protocol, patients were injected with 1 mL of hyaluronic acid filler in the lips and followed up at four and 12 weeks after injection. Lip volume, lip projection, and columella-labial angle were measured using a 3-dimensional imaging system at each time point. Follow-up values were compared with baseline. Compared with pre-treatment values, there was a statistically significant increase in mean lip volume and lip projection at four and 12 weeks after injection, with no significant differences between the two groups. Lips injected with hyaluronic acid filler of intermediate cross-link density resulted in more acute angles than lips injected with lightly cross-linked hyaluronic acid. The difference was statistically significant at each follow-up time point. No serious complications were observed throughout the study period. Our results imply that in patients who want a prominent upper lip lift, lip injections using hyaluronic acid fillers with intermediate cross-linking density can be a good option due to their lift capacity. The degree of cross-linking may not be a significant determinant of simple lip volume augmentation when other variables are constant.
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