Evidence map›Paper›PMID 35956059›Full record

ArticleJournal of clinical medicine2022

Utilizing Computed Tomography to Analyze the Morphomic Change between Patients with Localized and Metastatic Renal Cell Carcinoma: Body Composition Varies According to Cancer Stage.

Chin-Chieh Tan, Ting-Wen Sheng, Ying-Hsu Chang, Li-Jen Wang, Cheng-Keng Chuang, Chun-Te Wu, See-Tong Pang, I-Hung Shao

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Inflammation as a mediator between neck adipose tissue and tumor aggressiveness in hypopharyngeal and laryngeal squamous cell carcinoma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Chin-Chieh TanDepartment of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Ting-Wen ShengDepartment of Medical Imaging and Intervention, New Taipei Municipal Tu Cheng Hospital, Chang Gung Memorial Hospital, Chang Gung University, New Taipei City 236, Taiwan.ORCID 0000-0002-9645-3906
Ying-Hsu ChangDepartment of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Li-Jen WangDepartment of Medical Imaging and Intervention, New Taipei Municipal Tu Cheng Hospital, Chang Gung Memorial Hospital, Chang Gung University, New Taipei City 236, Taiwan.ORCID 0000-0002-2263-4835
Cheng-Keng ChuangDepartment of Medicine, Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0001-6154-1220
Chun-Te WuDepartment of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
See-Tong PangDepartment of Medicine, Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0002-2064-0828
I-Hung ShaoDepartment of Medicine, Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0002-4832-0113
Chang Gung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to elucidate the change of body composition in different clinical stages of renal cell carcinoma (RCC) by analyzing computed tomography (CT) images.

methodsWe enrolled patients diagnosed with RCC in a tertiary medical center who did not mention body weight loss or symptoms of cachexia. We grouped patients into those with localized RCC and those with metastatic RCC. Analyses of the volume of skeletal muscles tissue (SMT), subcutaneous adipose tissue (SAT), and visceral adipose tissue (VAT) calculated based on CT images were performed and included subgroup analyses by sex and age. The correlation between tumor size and body composition in localized RCC was also examined.

resultsA total of 188 patients were enrolled in this study. There was significantly lower VAT (

conclusionsIn localized RCC, VAT volume was significantly larger in those with large primary tumor size. However, the VAT was significantly lower in those with metastatic status comparing to those with localized disease. The clinical course of cancers closely correlates with body composition.

Indexed as

body compositioncomputed tomographyobesityrenal cell carcinomaskeletal musclesubcutaneous fatvisceral fat

Identifiers

PMID35956059
PMCPMC9369886
OpenAlexW4289176107

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.