Evidence map›Paper›PMID 35956031›Full record

ArticleJournal of clinical medicine2022

Increased T-bet/GATA-3 and ROR-γt /Foxp3 Ratios in Cerebrospinal Fluid as Potential Criteria for Definite Neuro-Behçet's Disease.

Meriam Belghith, Olfa Maghrebi, Aroua Cherif, Khadija Bahrini, Zakaria Saied, Samir Belal, Samia Ben Sassi, Mohamed-Ridha Barbouche, Mariem Kchaou

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Elevated Peripheral CD161ACR open rheumatology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Meriam BelghithLaboratory of Transmission, Control and Immunobiology of Infections, Institut Pasteur de Tunis, Tunis 1002, Tunisia.
Olfa MaghrebiLaboratory of Transmission, Control and Immunobiology of Infections, Institut Pasteur de Tunis, Tunis 1002, Tunisia.ORCID 0000-0002-8824-6659
Aroua CherifNeurological Department, Charles Nicolle Hospital, Tunis 1006, Tunisia.
Khadija BahriniLaboratory of Transmission, Control and Immunobiology of Infections, Institut Pasteur de Tunis, Tunis 1002, Tunisia.
Zakaria SaiedNeurology Department, Mongi Ben Hamida National Institute of Neurology, Tunis 1007, Tunisia.ORCID 0000-0002-4115-8758
Samir BelalNeurology Department, Mongi Ben Hamida National Institute of Neurology, Tunis 1007, Tunisia.
Samia Ben SassiNeurology Department, Mongi Ben Hamida National Institute of Neurology, Tunis 1007, Tunisia.
Mohamed-Ridha BarboucheLaboratory of Transmission, Control and Immunobiology of Infections, Institut Pasteur de Tunis, Tunis 1002, Tunisia.
Mariem KchaouNeurological Department, Charles Nicolle Hospital, Tunis 1006, Tunisia.
Institut Pasteur de Tunis · TNNational Institute of Neurology Mongi-Ben Hamida · TNHôpital Charles-Nicolle · TN

Funding

Tunisian Ministry for Higher Education, Research, and Technology LR16/IPT/02
6 · The paper itself

Abstract

When the central nervous system (CNS) is the primary affected site in an initial attack of Behçet's disease (BD), the differential diagnosis is particularly challenging. Some cases remain unclassified or qualified as probable neuro-Behçet's disease (NBD). Several cytokines are involved in the immunopathogenesis of this disease; however, studies establishing the differential cytokine pattern between probable and definite NBD are scarce. Twenty-eight parenchymal NBD patients, diagnosed according to the International Consensus Recommendation (ICR) criteria and classified into definite (D-NBD;

Indexed as

cerebrospinal fluidneuro-Behçet’s diseasePBMCsROR-γt/Foxp3T-bet/GATA-3

Identifiers

PMID35956031
PMCPMC9369407
OpenAlexW4289176740

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.