Evidence map›Paper›PMID 35956030›Full record

ArticleJournal of clinical medicine2022

Impact and Value of Hospital Antibiotic Stewardship: Retrospective Pre-COVID-19-Pandemic Analysis.

Maria Costantino, Valeria Conti, Graziamaria Corbi, Alessandra Anna Iannelli, Francesco Marongiu, Martina Torsiello, Antonio Della Vecchia, Carmine Sellitto, Armando Genovese, Giuseppina Moccia and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Maria CostantinoDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", 84081 Baronissi, Italy.
Valeria ContiDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", 84081 Baronissi, Italy.ORCID 0000-0001-6964-2739
Graziamaria CorbiDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-3441-889X
Alessandra Anna IannelliUniversity Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84121 Salerno, Italy.
Francesco MarongiuAssociation Non-Profit F.I.R.S.Thermae (Interdisciplinary Training, Researches and Spa Sciences), 80078 Naples, Italy.
Martina TorsielloDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", 84081 Baronissi, Italy.
Antonio Della VecchiaGeneral Directorate of Health Planning, Office 3-Italian Ministry of Health, 00144 Roma, Italy.
Carmine SellittoDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", 84081 Baronissi, Italy.ORCID 0000-0002-5595-7841
Armando GenoveseUniversity Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84121 Salerno, Italy.
Giuseppina MocciaDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", 84081 Baronissi, Italy.ORCID 0000-0002-7017-7413
Amelia FilippelliDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", 84081 Baronissi, Italy.ORCID 0000-0002-8235-9118
Francesco De CaroDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", 84081 Baronissi, Italy.ORCID 0000-0001-9659-9940
Ospedali Riuniti San Giovanni di Dio e Ruggi d'Aragona · ITMinistero della Salute · ITUniversity of Naples Federico II · ITUniversity of Salerno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aim"Antimicrobial stewardship" (AMS) is defined as a healthcare-system-wide approach to promoting and monitoring the judicious use of antimicrobials to preserve their future effectiveness. Therefore, we structured an observational study to monitor the hospital trend of antibiotic consumption and related expenditure before the COVID-19 pandemic and to evaluate how much AMS could affect this trend.

methodsThe research covered the antibiotic prescriptions at the University Hospital (U.H.) "San Giovanni di Dio e Ruggi d'Aragona", Salerno, Italy, comparing data on the therapies prescribed from 1 January to 31 December 2017 (27,384 patients) with those collected during the same period in 2019 (27,047 patients).

resultsUnlike national data, our results highlighted a decreasing trend in the consumption of antibiotics that did not concern only carbapenems and fluoroquinolones, but also the third-generation cephalosporins. Noteworthily, there was also a reduction in 2019 compared with 2017 in the consumption of colistin, an antibiotic towards which an increase in bacterial resistance in animals has been found nationally. In agreement with the national data, our research confirms a trend of an increase (+3.7%) in the total antibiotic consumption corresponding to more than 26% and 29% reductions in the total and therapy per-day costs, respectively.

conclusionsThe results show a positive impact of the AMS at the University Hospital "San Giovanni di Dio e Ruggi d'Aragona".

Indexed as

antibiotic resistanceAntimicrobial stewardshipCOVID-19

Identifiers

PMID35956030
PMCPMC9369048
OpenAlexW4289175774

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.