Evidence map›Paper›PMID 35955948›Full record

ArticleInternational journal of molecular sciences2022

Postnatal Protein Intake as a Determinant of Skeletal Muscle Structure and Function in Mice-A Pilot Study.

Ifigeneia Giakoumaki, Natalie Pollock, Turki Aljuaid, Anthony J Sannicandro, Moussira Alameddine, Euan Owen, Ioanna Myrtziou, Susan E Ozanne, Ioannis Kanakis, Katarzyna Goljanek-Whysall and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Ifigeneia GiakoumakiDepartment of Musculoskeletal & Ageing Science, Institute of Life Course & Medical Sciences, Faculty of Health & Life Sciences, University of Liverpool, Liverpool L7 8TX, UK.
Natalie PollockDepartment of Musculoskeletal & Ageing Science, Institute of Life Course & Medical Sciences, Faculty of Health & Life Sciences, University of Liverpool, Liverpool L7 8TX, UK.
Turki AljuaidDepartment of Physiology, School of Medicine and REMEDI, CMNHS, NUI Galway, H91 TK33 Galway, Ireland.
Anthony J SannicandroDepartment of Physiology, School of Medicine and REMEDI, CMNHS, NUI Galway, H91 TK33 Galway, Ireland.ORCID 0000-0002-8208-7343
Moussira AlameddineDepartment of Musculoskeletal & Ageing Science, Institute of Life Course & Medical Sciences, Faculty of Health & Life Sciences, University of Liverpool, Liverpool L7 8TX, UK.
Euan OwenDepartment of Musculoskeletal & Ageing Science, Institute of Life Course & Medical Sciences, Faculty of Health & Life Sciences, University of Liverpool, Liverpool L7 8TX, UK.
Ioanna MyrtziouChester Medical School, University of Chester, Bache Hall, Countess View, Chester CH2 1BR, UK.
Susan E OzanneUniversity of Cambridge MRC Metabolic Diseases Unit and Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Hospital Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0001-8753-5144
Ioannis KanakisDepartment of Musculoskeletal & Ageing Science, Institute of Life Course & Medical Sciences, Faculty of Health & Life Sciences, University of Liverpool, Liverpool L7 8TX, UK.ORCID 0000-0001-6410-1482
Katarzyna Goljanek-WhysallDepartment of Musculoskeletal & Ageing Science, Institute of Life Course & Medical Sciences, Faculty of Health & Life Sciences, University of Liverpool, Liverpool L7 8TX, UK.
Aphrodite VasilakiDepartment of Musculoskeletal & Ageing Science, Institute of Life Course & Medical Sciences, Faculty of Health & Life Sciences, University of Liverpool, Liverpool L7 8TX, UK.
University of Liverpool · GBUniversity of Chester · GBOllscoil na Gaillimhe – University of Galway · IETaif University · SAUniversity of Cambridge · GB

Funding

Biotechnology and Biological Sciences Research Council BB/L021668/1Medical Research Council MC_UU_00014/4Medical Research Council MR/P020941/1
6 · The paper itself

Abstract

Sarcopenia is characterised by an age-related decrease in the number of muscle fibres and additional weakening of the remaining fibres, resulting in a reduction in muscle mass and function. Many studies associate poor maternal nutrition during gestation and/or lactation with altered skeletal muscle homeostasis in the offspring and the development of sarcopenia. The aim of this study was to determine whether the musculoskeletal physiology in offspring born to mouse dams fed a low-protein diet during pregnancy was altered and whether any physiological changes could be modulated by the nutritional protein content in early postnatal stages. Thy1-YFP female mice were fed

Indexed as

LactationSarcopeniaAnimalsDiet, Protein-RestrictedFemaleHumansMaternal Nutritional Physiological PhenomenaMiceMuscle, SkeletalPilot ProjectsPregnancymaternal protein restrictionmicroRNAsneuromuscular junctionoffspringskeletal muscle

Identifiers

PMID35955948
PMCPMC9369224
OpenAlexW4295725733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.