ReviewInternational journal of molecular sciences2022
Pituitary Apoplexy: Risk Factors and Underlying Molecular Mechanisms.
Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- COVID19 infection and vaccination and the risk of pituitary apoplexy: an entangled yarn.Endocrine · 2025Pooled it
- Pituitary and COVID-19 vaccination: a systematic review.Pituitary · 2024Pooled it
- Pooled it
- Activated Macrophages Promote TNF-α-Associated Tumor Cell Necroptosis in Pituitary Apoplexy Through the PIEZO1-NFATC2/REL Axis.International journal of molecular sciences · 2026Article
- The emerging role of chemokines and chemokine receptors in the biological and clinical behaviour of pituitary neuroendocrine tumours: An exploratory transcriptomic study.Journal of neuroendocrinology · 2026Article
- Metabolomics identifies candidate diagnostic biomarkers for pituitary apoplexy.Frontiers in endocrinology · 2026Article
- A Nexus of Biomolecular Complexities in Pituitary Neuroendocrine Tumors: Insights into Key Molecular Drivers.Biomedicines · 2025Review
- A Brief Overview of Molecular Biology in Pituitary Adenomas with a Focus on Aggressive Lesions.International journal of molecular sciences · 2025Review
- An overview of hypopituitarism's causes.Frontiers in endocrinology · 2025Review
- Unveiling postpartum pituitary apoplexy through atypical presentation: A case report and review of literature.Radiology case reports · 2025Article
- Stiff-person syndrome mimic secondary to hypopituitarism: a case report and literature review.Frontiers in endocrinology · 2025Review
- Pituitary Apoplexy: An Updated Review.Journal of clinical medicine · 2024Review
- Medical and Surgical Approaches for a Non-functioning Pituitary Adenoma During Pregnancy.Cureus · 2024Article
- Article
- Sheehan Syndrome Unmasked by Adrenal Crisis Secondary to Severe Dengue Fever.Ochsner journal · 2024Article
- Challenges of Pituitary Apoplexy in Pregnancy.Journal of clinical medicine · 2023Review
- Perinatal asphyxia and hypothermic treatment from the endocrine perspective.Frontiers in endocrinology · 2023Review
- Risk Factors, Radiological and Clinical Outcomes in Subclinical and Clinical Pituitary Apoplexy.Journal of clinical medicine · 2022Article
- Pilot Findings on SARS-CoV-2 Vaccine-Induced Pituitary Diseases: A Mini Review from Diagnosis to Pathophysiology.Vaccines · 2022Review
- Risk factors for pituitary apoplexy: a meta-analysis and development of a clinical prediction nomogram.Frontiers in neurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pituitary apoplexy is a rare syndrome, graded from asymptomatic subclinical apoplexy to a life-threatening condition due to pituitary ischemia or haemorrhage of an enlarged pituitary gland. The risk factors and the molecular underlying mechanisms are yet to be elucidated. We provide an overview of the general concepts, the potential factors associated with pituitary adenoma susceptibility for apoplectic events and the molecular mechanisms that could be involved such as HIF-1α/VEGF pathways and metalloproteinases activation, among others. The knowledge of the molecular mechanisms that could participate in the pathogenesis of pituitary apoplexy is crucial to advancement in the identification of future diagnostic tools and therapeutic targets in this rare but sometimes fatal condition.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.