Evidence map›Paper›PMID 35955837›Full record

ArticleInternational journal of molecular sciences2022

Four Cholesterol-Recognition Motifs in the Pore-Forming and Translocation Domains of Adenylate Cyclase Toxin Are Essential for Invasion of Eukaryotic Cells and Lysis of Erythrocytes.

Jone Amuategi, Rocío Alonso, Helena Ostolaza

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jone AmuategiDepartment of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country UPV/EHU, 48080 Bilbao, Spain.
Rocío AlonsoFundación Biofísica Bizkaia (FBB), Barrio Sarriena s/n, 48940 Leioa, Spain.
Helena OstolazaDepartment of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country UPV/EHU, 48080 Bilbao, Spain.ORCID 0000-0002-2346-5228
University of the Basque Country · ESFundación Biofísica Bizkaia · ES

Funding

Spanish Ministerio de Economía y Competitividad BFU2017-82758-P
6 · The paper itself

Abstract

Adenylate Cyclase Toxin (ACT or CyaA) is one of the important virulence factors secreted by

Indexed as

Bordetella pertussisEukaryotic CellsAdenylate Cyclase ToxinCholesterolErythrocytesAdenylate Cyclase ToxinCholesterolbacterial toxinslipid-protein interactionspore-forming toxinsRTX toxins

Identifiers

PMID35955837
PMCPMC9369406
OpenAlexW4289866432

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.