ReviewInternational journal of molecular sciences2022
microRNAs: Key Players in Plant Response to Metal Toxicity.
Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 27 citations in OpenAlex.
- Non-coding RNAs as central regulators of phytohormone signaling in plant abiotic stress responses.Plant molecular biology · 2026Review
- Under heavy metal stress: genomic characterization and expression profiles of miRNA families in Phaseolus vulgaris.BMC plant biology · 2026Article
- Copper-molybdenum interactions in ruminant nutrition and reproductive physiology: mechanistic insights into growth, digestibility, and follicular development.Frontiers in veterinary science · 2026Review
- Identification and Characterization of Copper-Responsive miRNAs and Their Target Genes in Jerusalem Artichoke.Plants (Basel, Switzerland) · 2025Article
- Article
- MicroRNA Profiling in Non-model Plants Using Microarray Hybridization.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Impact of Heavy Metal Pollution in the Environment on the Metabolic Profile of Medicinal Plants and Their Therapeutic Potential.Plants (Basel, Switzerland) · 2024Review
- Mechanisms of Plant Epigenetic Regulation in Response to Plant Stress: Recent Discoveries and Implications.Plants (Basel, Switzerland) · 2024Review
- Chromium toxicity, speciation, and remediation strategies in soil-plant interface: A critical review.Frontiers in plant science · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 3 institutions in 2 countries.
Funding
Abstract
Environmental metal pollution is a common problem threatening sustainable and safe crop production. Heavy metals (HMs) cause toxicity by targeting key molecules and life processes in plant cells. Plants counteract excess metals in the environment by enhancing defense responses, such as metal chelation, isolation to vacuoles, regulating metal intake through transporters, and strengthening antioxidant mechanisms. In recent years, microRNAs (miRNAs), as a small non-coding RNA, have become the central regulator of a variety of abiotic stresses, including HMs. With the introduction of the latest technologies such as next-generation sequencing (NGS), more and more miRNAs have been widely recognized in several plants due to their diverse roles. Metal-regulated miRNAs and their target genes are part of a complex regulatory network. Known miRNAs coordinate plant responses to metal stress through antioxidant functions, root growth, hormone signals, transcription factors (TF), and metal transporters. This article reviews the research progress of miRNAs in the stress response of plants to the accumulation of HMs, such as Cu, Cd, Hg, Cr, and Al, and the toxicity of heavy metal ions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.