Evidence map›Paper›PMID 35955737›Full record

ArticleInternational journal of molecular sciences2022

Downregulation of IL-8 and IL-10 by the Activation of Ca

Susumu Ohya, Miki Matsui, Junko Kajikuri, Hiroaki Kito, Kyoko Endo

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Transcriptional Repression of CCL2 by KInternational journal of molecular sciences · 2025
    Article
  7. Calcium channels as pharmacological targets for cancer therapy.Clinical and experimental medicine · 2025
    Review
  8. Article
  9. Article
  10. Down-Regulation of CYP3A4 by the KInternational journal of molecular sciences · 2023
    Article
  11. Recent Developments in Ion Channel and Ion-Related Signaling.International journal of molecular sciences · 2023
    Article
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Susumu OhyaDepartment of Pharmacology, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, Japan.ORCID 0000-0002-5765-0667
Miki MatsuiDepartment of Pharmacology, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, Japan.
Junko KajikuriDepartment of Pharmacology, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, Japan.ORCID 0000-0003-0598-0733
Hiroaki KitoDepartment of Pharmacology, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, Japan.
Kyoko EndoDepartment of Pharmacology, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, Japan.
Nagoya City University · JP

Funding

Bristol-Myers Squibb foundation 53952417Japan Society for the Promotion of Science JP20K07071
6 · The paper itself

Abstract

THP-1-differentiated macrophages are useful for investigating the physiological significance of tumor-associated macrophages (TAMs). In the tumor microenvironment (TME), TAMs with the M

Indexed as

Interleukin-10NeoplasmsDown-RegulationHumansInterleukin-8Intermediate-Conductance Calcium-Activated Potassium ChannelsMacrophagesTumor MicroenvironmentInterleukin-10Interleukin-8Intermediate-Conductance Calcium-Activated Potassium ChannelsKCNN4 protein, humanIL-10IL-8KCa3.1K+ channelTHP-1tumor-associated macrophagetumor microenvironment

Identifiers

PMID35955737
PMCPMC9368915
OpenAlexW4289711772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.