Evidence map›Paper›PMID 35955705›Full record

ArticleInternational journal of molecular sciences2022

Predicting the Prognostic Value of

Xuan Xu, Majid Jaberi-Douraki, Nicholas A Wallace

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Xuan XuDivision of Biology, Kansas State University, Manhattan, KS 66506, USA.ORCID 0000-0003-3349-7183
Majid Jaberi-Douraki1DATA Consortium, Kansas State University Olathe, Olathe, KS 66061, USA.ORCID 0000-0002-8505-6550
Nicholas A WallaceDivision of Biology, Kansas State University, Manhattan, KS 66506, USA.ORCID 0000-0002-3971-716X
Kansas State University · US

Funding

Mentoring CoreP20GM103418 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Douglas E Wright · 2012 to 2026
$63.0M
Sex-specific effects of obestity on Influenza A virus infection and immunityP20GM130448 · NIGMS · KANSAS STATE UNIVERSITY · PI Juergen A Richt · 2020 to 2026
$15.8M
HPV Oncogenes Dysregulate Translesion SynthesisR15CA242057 · NCI · KANSAS STATE UNIVERSITY · PI WALLACE, NICHOLAS A · 2020 to 2020
$454k
BioNexus KC 20-7 Nexus of Animal and Human Health Research GrantJohnson Cancer Research Center Johnson Cancer Research Center in Kansas State UniversityNCI NIH HHS NCI R15 CA242057 01A1NIGMS NIH HHS P20 GM103418NIGMS NIH HHS P20GM130448United States Department of Defense CMDRP PRCRP CA160224
6 · The paper itself

Abstract

Translesion synthesis (TLS) is a cell signaling pathway that facilitates the tolerance of replication stress. Increased TLS activity, the particularly elevated expression of TLS polymerases, has been linked to resistance to cancer chemotherapeutics and significantly altered patient outcomes. Building upon current knowledge, we found that the expression of one of these TLS polymerases (

Indexed as

DNA-Directed DNA PolymerasePancreatic NeoplasmsDNA ReplicationFemaleHumansMachine LearningPrognosisDNA-Directed DNA Polymerasecancer survivalgene associationgene regulatory networkmachine learningpolymerase iota

Identifiers

PMID35955705
PMCPMC9369001
OpenAlexW4289520029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.