Evidence map›Paper›PMID 35954689›Full record

ArticleInternational journal of environmental research and public health2022

Multimorbidity Patterns among People with Type 2 Diabetes Mellitus: Findings from Lima, Peru.

Antonio Bernabe-Ortiz, Diego B Borjas-Cavero, Jimmy D Páucar-Alfaro, Rodrigo M Carrillo-Larco

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Antonio Bernabe-OrtizCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima 15074, Peru.ORCID 0000-0002-6834-1376
Diego B Borjas-CaveroHospital de Emergencias Villa El Salvador, Lima 15837, Peru.ORCID 0000-0002-2316-7810
Jimmy D Páucar-AlfaroHospital de Emergencias Villa El Salvador, Lima 15837, Peru.
Rodrigo M Carrillo-LarcoCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima 15074, Peru.ORCID 0000-0002-2090-1856
Universidad Peruana Cayetano Heredia · PE

Funding

Wellcome TrustWellcome Trust 214185/Z/18/Z
6 · The paper itself

Abstract

backgroundType 2 diabetes (T2DM) is a chronic condition with a high disease burden worldwide, and individuals with T2DM often have other morbidities. Understanding the local multimorbidity profile of patients with T2DM will inform precision medicine and public health, so that tailored interventions can be offered according to the different profiles.

methodsAn analysis was conducted of electronic health records (2016-2021) in one hospital in Lima, Peru. Based on ICD-10 codes and the available measurements (e.g., body mass index), we identified all T2DM cases and quantified the frequency of the most common comorbidities (those in ≥1% of the sample). We also conducted k-means analysis that was informed by the most frequent comorbidities, to identify clusters of patients with T2DM and other chronic conditions.

resultsThere were 9582 individual records with T2DM (mean age 58.6 years, 61.5% women). The most frequent chronic conditions were obesity (29.4%), hypertension (18.8%), dyslipidemia (11.3%), hypothyroidism (6.4%), and arthropathy (3.6%); and 51.6% had multimorbidity: 32.8% had only one, 14.1% had two, and 4.7% had three or more extra chronic conditions in addition to T2DM. The cluster analysis revealed four unique groups: T2DM with no other chronic disease, T2DM with obesity only, T2DM with hypertension but without obesity, and T2DM with all other chronic conditions.

conclusionsMore than one in two people with T2DM had multimorbidity. Obesity, hypertension, and dyslipidemia were the most common chronic conditions that were associated with T2DM. Four clusters of chronic morbidities were found, signaling mutually exclusive profiles of patients with T2DM according to their multimorbidity profile.

Indexed as

Diabetes Mellitus, Type 2DyslipidemiasHypertensionChronic DiseaseFemaleHumansMaleMiddle AgedMultimorbidityObesityPeruelectronic health recordsk-meansphenotypesType 2 diabetes mellitus

Identifiers

PMID35954689
PMCPMC9367906
OpenAlexW4289134218

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.