ArticleInternational journal of environmental research and public health2022
Fatigue and Arousal Modulations Revealed by Saccade and Pupil Dynamics.
Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 28 citations in OpenAlex.
- Autonomic Dysregulation in Obsessive-Compulsive Disorder: Simultaneous Assessment of Electrodermal, Cardiac, and Oculomotor Responses to Triggering Videos-An Exploratory Study.Brain sciences · 2026Article
- Comparing masking and habituation roles in saccadic omission of stimuli optimized for intra-saccadic vision.Journal of vision · 2026Article
- The evolution of fatigue in remote tower controllers: evidence from eye-tracking analysis.Scientific reports · 2026Article
- Characterizing alterations in attention networks under high mental workload.Scientific reports · 2026Article
- Mental fatigue in football: methodology and experimental protocol.Frontiers in sports and active living · 2026Article
- Impact of post stroke fatigue on saccadic eye movement control and learning through inflammatory mechanisms.Scientific reports · 2025Article
- Reading Assessment and Eye Movement Analysis in Bilateral Central Scotoma Due to Age-Related Macular Degeneration.Journal of eye movement research · 2025Article
- Disentangling the Neural Circuits of Arousal and Anxiety-Like Behavior.Current topics in behavioral neurosciences · 2025Review
- Effects of binocularity and eye dominance on visually-driven ocular tracking.Frontiers in neuroscience · 2025Article
- Time-on-task effects on human pupillary and saccadic metrics after theta burst transcranial magnetic stimulation over the frontal eye field.IBRO neuroscience reports · 2023Article
- Emotion Detection Based on Pupil Variation.Healthcare (Basel, Switzerland) · 2023Article
- Investigating the role of human frontal eye field in the pupil light reflex modulation by saccade planning and working memory.Frontiers in human neuroscience · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Saccadic eye movements are directed to the objects of interests and enable high-resolution visual images in the exploration of the visual world. There is a trial-to-trial variation in saccade dynamics even in a simple task, possibly attributed to arousal fluctuations. Previous studies have showed that an increase of fatigue level over time, also known as time-on-task, can be revealed by saccade peak velocity. In addition, pupil size, controlled by the autonomic nervous system, has long been used as an arousal index. However, limited research has been done with regards to the relation between pupil size and saccade behavior in the context of trial-to-trial variation. To investigate fatigue and arousal effects on saccadic and pupillary responses, we used bright and emotional stimuli to evoke pupillary responses in tasks requiring reactive and voluntary saccade generation. Decreased voluntary saccade peak velocities, reduced tonic pupil size and phasic pupillary responses were observed as time-on-task increased. Moreover, tonic pupil size affected saccade latency and dynamics, with steeper saccade main sequence slope as tonic pupil size increased. In summary, saccade dynamics and tonic pupil size were sensitive to fatigue and arousal level, together providing valuable information for the understanding of human behavior.
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Registered trials
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