Evidence map›Paper›PMID 35954484›Full record

ReviewCancers2022

How Gut Microbiota Are Shaped by Pattern Recognition Receptors in Colitis and Colorectal Cancer.

Furong Qing, Tao Xie, Lu Xie, Tianfu Guo, Zhiping Liu

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. A Putative Role ofMicroorganisms · 2023
    Review
  8. Microbiota regulation in constipation and colorectal cancer.World journal of gastrointestinal oncology · 2023
    Review
  9. Review
  10. The research progress in the interaction betweenFrontiers in microbiology · 2022
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Furong QingCenter for Immunology, Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Gannan Medical University, Ganzhou 341000, China.
Tao XieCenter for Scientific Research, Gannan Medical University, Ganzhou 341000, China.
Lu XieSchool of Basic Medicine, Gannan Medical University, Ganzhou 341000, China.
Tianfu GuoSchool of Basic Medicine, Gannan Medical University, Ganzhou 341000, China.
Zhiping LiuCenter for Immunology, Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Gannan Medical University, Ganzhou 341000, China.ORCID 0000-0002-5109-4153
Gannan Medical University · CN

Funding

Inflammation and Immunology Research Team of Gannan Medical University TD2021JC01Jianggang Scholor of Jiangxi Province QD202205National Natural Science Foundation of China 31960163Natural Science Foundation of Jiangxi Province 20171ACB20024
6 · The paper itself

Abstract

Disorders of gut microbiota have been closely linked to the occurrence of various intestinal diseases including colitis and colorectal cancer (CRC). Specifically, the production of beneficial bacteria and intestinal metabolites may slow the development of some intestinal diseases. Recently, it has been proposed that pattern recognition receptors (PRRs) not only recognize pathogens and initiate inflammatory signal transduction to induce immune responses but also influence the composition of intestinal microorganisms. However, the mechanisms through which PRRs regulate gut microbiota in the setting of colitis and CRC have rarely been systematically reviewed. Therefore, in this paper, we summarize recent advances in our understanding of how PRRs shape gut microbiota and how this influences the development of colitis and CRC.

Indexed as

colitiscolorectal cancergut microbiotaintestinal epitheliumpattern recognition receptor

Identifiers

PMID35954484
PMCPMC9367250
OpenAlexW4290465835

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.