Evidence map›Paper›PMID 35954386›Full record

ArticleCancers2022

The Construction and Validation of Nomogram to Predict the Prognosis with Small-Cell Lung Cancer Followed Surgery.

Lei-Lei Wu, Wu-Tao Chen, Chong-Wu Li, Si-Hui Song, Shu-Quan Xu, Sheng-Peng Wan, Zhi-Yuan Liu, Wei-Kang Lin, Kun Li, Zhi-Xin Li and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Lei-Lei WuDepartment of Thoracic Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai 200433, China.ORCID 0000-0002-7417-6864
Wu-Tao ChenSchool of Medicine, Shanghai Jiao Tong University, No. 227 South Chongqing Road, Shanghai 200025, China.
Chong-Wu LiDepartment of Thoracic Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai 200433, China.
Si-Hui SongSchool of Medicine, Tongji University, Shanghai 200092, China.
Shu-Quan XuSchool of Medicine, Tongji University, Shanghai 200092, China.
Sheng-Peng WanSchool of Medicine, Tongji University, Shanghai 200092, China.
Zhi-Yuan LiuSchool of Medicine, Tongji University, Shanghai 200092, China.
Wei-Kang LinDepartment of Thoracic Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai 200433, China.
Kun LiDepartment of Thoracic Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai 200433, China.
Zhi-Xin LiDepartment of Thoracic Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai 200433, China.ORCID 0000-0002-6292-3412
Dong XieDepartment of Thoracic Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai 200433, China.ORCID 0000-0002-3715-1801
Tongji University · CNShanghai Jiao Tong University · CN

Funding

Outstanding Young Medical Talent of Rising Star in Medical Garden of Shanghai Municipal Health Commission "Dong Xie" "Dong Xie"Science and Technology Commission of Shanghai Municipality 1Y11913400Shanghai Pulmonary Hospital Foundation FKXR1904Shanghai ShenKang Hospital Development Centre SHDC22020218
6 · The paper itself

Abstract

This study constructed and validated a prognostic model to evaluate the survival of small-cell lung cancer (SCLC) patients following surgery, and shed light on the strategy of postoperative radiotherapy. A total of 882 patients from Shanghai Pulmonary Hospital and the Surveillance, Epidemiology and End Results database after lung resection were selected. Multivariable Cox analysis was used to identify the indicators affecting long-term survival in patients. A nomogram was constructed to predict the prognosis of eligible patients. Indices of concordance (C-index) was used to access the predictive ability of cancer-specific survival (CSS) for the prognostic model. CSS discrimination in the prognostic model was comparable in the training and validation cohorts (C-index = 0.637[NORAD-T], 0.660[NORAD-V], 0.656[RAD] and 0.627[our hospital], respectively. Stratification based on the cutoff value of the nomogram yielded low- and high-risk subgroups in four cohorts. For patients in the high-risk group, postoperative radiotherapy was considered a survival-promoting strategy (unadjusted HR 0.641, 95% CI 0.469-0.876,

Indexed as

nomogrampostoperative radiotherapysmall-cell lung cancersurgerysurvival

Identifiers

PMID35954386
PMCPMC9367260
OpenAlexW4289110199

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.