Evidence map›Paper›PMID 35954303›Full record

ReviewCells2022

Endogenous Retroviruses and Placental Evolution, Development, and Diversity.

Kazuhiko Imakawa, Kazuya Kusama, Tomoko Kaneko-Ishino, So Nakagawa, Koichi Kitao, Takayuki Miyazawa, Fumitoshi Ishino

Abstract readReview
In one paragraph

Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Review
  3. Rethinking One Health: Microbial Foundations for Ecological Governance.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Genetic Diversity in theBiomolecules · 2025
    Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Paternal Expressed Gene 10 (PEG10) is decreased in early-onset preeclampsia.Reproductive biology and endocrinology : RB&E · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kazuhiko ImakawaResearch Institute of Agriculture, Tokai University, Kumamoto 862-8652, Japan.ORCID 0000-0002-3798-3560
Kazuya KusamaDepartment of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan.ORCID 0000-0002-9120-0475
Tomoko Kaneko-IshinoSchool of Medicine, Tokai University, Tokyo 259-1193, Japan.
So NakagawaDepartment of Molecular Life Science, Tokai University School of Medicine, Nakagawa 259-1193, Japan.ORCID 0000-0003-1760-3839
Koichi KitaoLaboratory of Virus-Host Coevolution, Institute for Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.ORCID 0000-0002-2860-2834
Takayuki MiyazawaLaboratory of Virus-Host Coevolution, Institute for Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.
Fumitoshi IshinoInstitute of Research, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.ORCID 0000-0001-8458-6069

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The main roles of placentas include physical protection, nutrient and oxygen import, export of gasses and fetal waste products, and endocrinological regulation. In addition to physical protection of the fetus, the placentas must provide immune protection throughout gestation. These basic functions are well-conserved; however, placentas are undoubtedly recent evolving organs with structural and cellular diversities. These differences have been explained for the last two decades through co-opting genes and gene control elements derived from transposable elements, including endogenous retroviruses (ERVs). However, the differences in placental structures have not been explained or characterized. This manuscript addresses the sorting of ERVs and their integration into the mammalian genomes and provides new ways to explain why placental structures have diverged.

Indexed as

Endogenous RetrovirusesAnimalsDNA Transposable ElementsFemaleMammalsPlacentaPregnancyDNA Transposable Elementsendogenous retrovirus (ERV)mammalsplacentastructural diversity

Identifiers

PMID35954303
PMCPMC9367772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.