Evidence map›Paper›PMID 35954286›Full record

ArticleCells2022

lncRNA2919 Suppresses Rabbit Dermal Papilla Cell Proliferation via

Bohao Zhao, Jiali Li, Ming Liu, Shuaishuai Hu, Naisu Yang, Shuang Liang, Xiyu Zhang, Yingying Dai, Zhiyuan Bao, Yang Chen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Bohao ZhaoCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Jiali LiCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Ming LiuCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Shuaishuai HuCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Naisu YangCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Shuang LiangCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Xiyu ZhangCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Yingying DaiCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Zhiyuan BaoCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Yang ChenCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Xinsheng WuCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0001-9871-0251
Yangzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hair follicles (HFs) are complex organs that grow cyclically during mammals' growth and development. Long non-coding RNAs (lncRNAs) cannot be translated into proteins and play crucial roles in many biological processes. In our previous study, candidate lncRNAs associated with HF cyclic regeneration were screened, and we identified that the novel lncRNA, lncRNA2919, was significantly expressed during catagen. Here, we identified that lncRNA2919 has no coding potentiality and is highly expressed in the cell nucleus, and downregulates HF growth and development-related genes, inhibits cell proliferation, and promotes cell apoptosis in rabbit dermal papilla cells. lncRNA2919 recruits STAT1 to form a compound. As a key transcription factor, STAT1 regulates the transcriptional expression of KRTAP11-1. Our study revealed that lncRNA2919 is involved in HF cyclic regeneration through the

Indexed as

RNA, Long NoncodingAnimalsCell ProliferationGene Expression RegulationHairHair FollicleHumansMammalsRabbitsRNA, Long Noncodingdermal papilla cellshair follicle growth and developmentKRTAP11-1lncRNA2919STAT1trans regulation

Identifiers

PMID35954286
PMCPMC9368379
OpenAlexW4290467000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.