Evidence map›Paper›PMID 35954249›Full record

ReviewCells2022

ATP-Sensitive Potassium Channels in Migraine: Translational Findings and Therapeutic Potential.

Amalie Clement, Song Guo, Inger Jansen-Olesen, Sarah Louise Christensen

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. The therapeutic pipeline in migraine: What does the future hold?Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Review
  3. Review
  4. Nicorandil-induced Isolated Abducens Nerve Palsy.Internal medicine (Tokyo, Japan) · 2025
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Future targets for migraine treatment beyond CGRP.The journal of headache and pain · 2023
    Review
  15. Review
  16. Pharmacological Profiling of KPharmaceuticals (Basel, Switzerland) · 2023
    Article
  17. The ATP sensitive potassium channel (KFrontiers in molecular neuroscience · 2023
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Amalie ClementGlostrup Research Institute, Department of Neurology, Danish Headache Center, Copenhagen University Hospital-Rigshospitalet, Nordstjernevej 42, Glostrup, 2600 Copenhagen, Denmark.ORCID 0000-0002-1301-9291
Song GuoGlostrup Research Institute, Department of Neurology, Danish Headache Center, Copenhagen University Hospital-Rigshospitalet, Nordstjernevej 42, Glostrup, 2600 Copenhagen, Denmark.
Inger Jansen-OlesenGlostrup Research Institute, Department of Neurology, Danish Headache Center, Copenhagen University Hospital-Rigshospitalet, Nordstjernevej 42, Glostrup, 2600 Copenhagen, Denmark.
Sarah Louise ChristensenGlostrup Research Institute, Department of Neurology, Danish Headache Center, Copenhagen University Hospital-Rigshospitalet, Nordstjernevej 42, Glostrup, 2600 Copenhagen, Denmark.ORCID 0000-0002-7985-4783
Glostrup Hospital · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Globally, migraine is a leading cause of disability with a huge impact on both the work and private life of affected persons. To overcome the societal migraine burden, better treatment options are needed. Increasing evidence suggests that ATP-sensitive potassium (K

Indexed as

KATP ChannelsMigraine DisordersAdenosine TriphosphateCromakalimHeadacheHumansVasodilator AgentsAdenosine TriphosphateCromakalimKATP ChannelsVasodilator Agentsglibenclamidehuman migraine modelin vivo modelsKATP channelsKir6.xlevcromakalimmigraineprovoked migraineSUR

Identifiers

PMID35954249
PMCPMC9367966
OpenAlexW4289985687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.