Evidence map›Paper›PMID 35954231›Full record

ArticleCells2022

Modeling MEN1 with Patient-Origin iPSCs Reveals GLP-1R Mediated Hypersecretion of Insulin.

Ziqi Cheng, Dongsheng Guo, Aynisahan Ruzi, Tingcai Pan, Kai You, Yan Chen, Xinping Huang, Jiaye Zhang, Fan Yang, Lizhi Niu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Ziqi ChengCenter for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China.
Dongsheng GuoCenter for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China.ORCID 0000-0002-9702-7327
Aynisahan RuziCenter for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China.
Tingcai PanCenter for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China.
Kai YouCenter for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China.
Yan ChenCenter for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China.
Xinping HuangCenter for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China.ORCID 0000-0002-3110-2128
Jiaye ZhangCenter for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China.
Fan YangMinistry of Education CNS Regeneration Collaborative Joint Laboratory, Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou 510632, China.
Lizhi NiuGuangzhou Fuda Cancer Hospital, Guangzhou 510305, China.
Kecheng XuGuangzhou Fuda Cancer Hospital, Guangzhou 510305, China.
Yin-Xiong LiCenter for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China.
Chinese Academy of Sciences · CNFuda Cancer Hospital · CNJinan University · CN

Funding

Environmental Health Perspectives, NIEHS27302C0031 · NIEHS · 2008 to 2008
$1.2M
NIEHS NIH HHS 27302C0031
6 · The paper itself

Abstract

Multiple endocrine neoplasia type 1 (MEN1) is an inherited disease caused by mutations in the

Indexed as

Induced Pluripotent Stem CellsMultiple Endocrine Neoplasia Type 1Neuroectodermal Tumors, PrimitiveAnimalsGlucagon-Like Peptide-1 ReceptorHumansInsulinInsulin, Regular, HumanMicePhosphatidylinositol 3-KinasesProto-Oncogene ProteinsGlucagon-Like Peptide-1 ReceptorInsulinInsulin, Regular, HumanMen1 protein, mousePhosphatidylinositol 3-KinasesProto-Oncogene Proteinsdisease modelingGLP-1RhyperinsulinemiaMEN1β-cell differentiation

Identifiers

PMID35954231
PMCPMC9368616
OpenAlexW4289517294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.