Evidence map›Paper›PMID 35954185›Full record

ArticleCells2022

A Comparative Analysis of Mucus Immunomodulatory Properties from Seven Marine Gastropods from the Mediterranean Sea.

Clementina Sansone, Cecilia Balestra, Luigi Pistelli, Angelo Del Mondo, David Osca, Christophe Brunet, Fabio Crocetta

Abstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Clementina SansoneDepartment of Marine Biotechnology, Stazione Zoologica Anton Dohrn, Villa Comunale, I-80121 Napoli, Italy.ORCID 0000-0002-3007-8154
Cecilia BalestraDepartment of Marine Biotechnology, Stazione Zoologica Anton Dohrn, Villa Comunale, I-80121 Napoli, Italy.ORCID 0000-0003-4433-4793
Luigi PistelliDepartment of Marine Biotechnology, Stazione Zoologica Anton Dohrn, Villa Comunale, I-80121 Napoli, Italy.ORCID 0000-0003-2638-2935
Angelo Del MondoDepartment of Marine Biotechnology, Stazione Zoologica Anton Dohrn, Villa Comunale, I-80121 Napoli, Italy.ORCID 0000-0002-7983-0861
David OscaDepartment of Integrative Marine Ecology, Stazione Zoologica Anton Dohrn, Villa Comunale, I-80121 Napoli, Italy.ORCID 0000-0001-5259-9420
Christophe BrunetDepartment of Marine Biotechnology, Stazione Zoologica Anton Dohrn, Villa Comunale, I-80121 Napoli, Italy.
Fabio CrocettaDepartment of Integrative Marine Ecology, Stazione Zoologica Anton Dohrn, Villa Comunale, I-80121 Napoli, Italy.ORCID 0000-0002-2800-3735

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The treatment of inflammatory and immune-related diseases due to dysfunctioning of the immune system necessitates modulation of the immune response through immunomodulatory compounds. Marine environments are considered as a new frontier for health benefit product implementations. Marine biodiversity is still a low explored resource, despite it is expected to represent an important platform for chemical bioactive compounds. Within the phylum Mollusca, gastropods are known to synthetize mucus, the latter presenting relevant bioactive properties, e.g., related to immunomodulant molecules able to activate the innate and acquired immune system. This study proposes a bioprospecting of the immunomodulant activity of mucus isolated from seven common gastropod species from the Gulf of Naples (Mediterranean Sea). Results showed that not all mucus displayed a significant cytotoxic activity on the two human cancer cell lines A549 and A2058. On the other hand, the mucus from

Indexed as

GastropodaAnimalsBiodiversityHumansImmunityMediterranean SeaMucusgastropods’ mucusimmunomodulationmarine biotechnologymonocytes’ differentiation

Identifiers

PMID35954185
PMCPMC9367618

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.