Evidence map›Paper›PMID 35954183›Full record

ArticleCells2022

MiR-23b Promotes Porcine Preadipocyte Differentiation via

Meng Li, Na Zhang, Jiao Li, Wanfeng Zhang, Wei Hei, Mengting Ji, Yang Yang, Guoqing Cao, Xiaohong Guo, Bugao Li

Abstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Sequence variants associated with resilient responses in growing pigs.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2025
    Article
  3. Article
  4. Genome-Wide Analysis Reveals Copy Number Variant GeneAnimals : an open access journal from MDPI · 2024
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Meng LiCollege of Animal Science, Shanxi Agricultural University, Taigu 030801, China.
Na ZhangCollege of Animal Science, Shanxi Agricultural University, Taigu 030801, China.
Jiao LiCollege of Animal Science, Shanxi Agricultural University, Taigu 030801, China.
Wanfeng ZhangCollege of Animal Science, Shanxi Agricultural University, Taigu 030801, China.
Wei HeiCollege of Animal Science, Shanxi Agricultural University, Taigu 030801, China.
Mengting JiCollege of Animal Science, Shanxi Agricultural University, Taigu 030801, China.
Yang YangCollege of Animal Science, Shanxi Agricultural University, Taigu 030801, China.
Guoqing CaoCollege of Animal Science, Shanxi Agricultural University, Taigu 030801, China.
Xiaohong GuoCollege of Animal Science, Shanxi Agricultural University, Taigu 030801, China.
Bugao LiCollege of Animal Science, Shanxi Agricultural University, Taigu 030801, China.ORCID 0000-0002-3844-3726

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic improvement of pork quality is one of the hot topics in pig germplasm innovation. Backfat thickness and intramuscular fat content are important indexes of meat quality. MiRNAs are becoming recognized as a crucial regulator of adipose development. Therefore, it is crucial to understand how miR-23b regulates fat metabolism at the molecular level. In the present study, Oil Red O staining, and Western blot were used to evaluate the effect of miR-23b on the differentiation of porcine preadipocytes. Dual-luciferase reporter gene assay, pulldown, and RIP were used to reveal the mechanism of miR-23b regulating cell differentiation. The findings demonstrated that miR-23b promotes the expression of adipogenic factors and increases the content of lipid droplets, thus promoting the differentiation of preadipocytes. Further research found that miR-23b can directly bind to the 3'UTR of

Indexed as

AdipocytesMicroRNAs3' Untranslated RegionsAdipogenesisAnimalsCell DifferentiationSwine3' Untranslated RegionsMicroRNAsACSL4adipogenic differentiationmiR-23bpigpreadipocyteSESN3

Identifiers

PMID35954183
PMCPMC9367261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.