Evidence map›Paper›PMID 35954176›Full record

ReviewCells2022

MicroRNAs and Their Big Therapeutic Impacts: Delivery Strategies for Cancer Intervention.

Charles Holjencin, Andrew Jakymiw

Abstract readReview
In one paragraph

Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  20. Nucleic acid drugs: recent progress and future perspectives.Signal transduction and targeted therapy · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Charles HoljencinDepartment of Oral Health Sciences, James B. Edwards College of Dental Medicine, Medical University of South Carolina (MUSC), Charleston, SC 29425, USA.ORCID 0000-0002-1254-8626
Andrew JakymiwDepartment of Oral Health Sciences, James B. Edwards College of Dental Medicine, Medical University of South Carolina (MUSC), Charleston, SC 29425, USA.

Funding

Translational Science Laboratory Shared ResourceP30CA138313 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI John J Lemasters · 2009 to 2026
$42.7M
South Carolina Clinical & Translational Research Institute (SCTR)UL1TR001450 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T., FLUME, PATRICK A · 2015 to 2024
$41.1M
T-COHR: Training in Craniofacial and Oral Health ResearchT32DE017551 · NIDCR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI YAO, HAI · 2006 to 2025
$10.3M
Stereochemical and dual peptide siRNA-carrier complexes for oral cancer therapyR21DE027231 · NIDCR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI JAKYMIW, ANDREW GEORGE · 2017 to 2018
$411k
NCATS NIH HHS UL1 TR001450NCI NIH HHS P30 CA138313NIDCR NIH HHS R21 DE027231NIDCR NIH HHS T32 DE017551
6 · The paper itself

Abstract

Three decades have passed from the initial discovery of a microRNA (miRNA) in

Indexed as

MicroRNAsNeoplasmsNucleic AcidsHumansPeptidesPolymersMicroRNAsNucleic AcidsPeptidesPolymerscancercell-penetrating peptidesCPPsmicroRNAmiRNA deliverymiRNA therapeuticsRNA silencing

Identifiers

PMID35954176
PMCPMC9367537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.