Evidence map›Paper›PMID 35953985›Full record

ArticleAnimals : an open access journal from MDPI2022

Evaluation of the Effect of Storage Time on ROTEM S

Nicole Weingand, Johanna Vuille-Dit-Bille, Rahel Jud Schefer, Annette P N Kutter, Martina Stirn, Katja-Nicole Adamik, Nadja E Sigrist

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Evaluation of the Effect of Induced Endotoxemia on ROTEM SAnimals : an open access journal from MDPI · 2023
    Article
  3. Article
  4. The establishment of reference intervals for the ClotPro thromboelastometry device in healthy dogs.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nicole WeingandDepartment for Small Animals, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland.
Johanna Vuille-Dit-BilleDepartment of Clinical Veterinary Science, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.
Rahel Jud ScheferDepartment for Small Animals, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland.
Annette P N KutterDepartment for Clinical Diagnostics and Services, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland.ORCID 0000-0003-2434-0141
Martina StirnDepartment for Clinical Diagnostics and Services, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland.
Katja-Nicole AdamikDepartment of Clinical Veterinary Science, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.
Nadja E SigristDepartment for Small Animals, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland.ORCID 0000-0002-9540-3288

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viscoelastic testing as a bedside test to assess global haemostasis has gained popularity in the past decade, with rotational thromboelastometry (ROTEM) and thromboelastography (TEG) being the two commonly used devices. TEG studies suggest analysis 30 min after blood sampling. However, the reproducibility of results over time for ROTEM analysis using lyophilized samples in dogs has not been established. In this study, we investigated the influence of time on viscoelastic testing, using 33 healthy staff-/client-owned dogs for blood sampling and repeated measurements of ROTEM tracings at three different time points after blood collection. Additionally, a group of 21 hospitalized patients with suspected coagulation disorders were included to investigate whether stability over time was comparable between healthy and ill dogs. We demonstrated a significant difference of ROTEM tracings over time, with a tendency towards hypocoagulability over time. These changes do have a clinical relevance as they exceed reference intervals and could therefore lead to erroneous conclusions about a patient's coagulation status. Therefore, time-specific reference intervals are proposed and presented in this publication.

Indexed as

canineEx-TEMFib-TEMIn-TEMreference intervalthromboelastometry

Identifiers

PMID35953985
PMCPMC9367567

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.