Evidence map›Paper›PMID 35953837›Full record

ArticleJournal of nanobiotechnology2022

Iron oxide@chlorophyll clustered nanoparticles eliminate bladder cancer by photodynamic immunotherapy-initiated ferroptosis and immunostimulation.

Yu-Cheng Chin, Li-Xing Yang, Fei-Ting Hsu, Che-Wei Hsu, Te-Wei Chang, Hsi-Ying Chen, Linda Yen-Chien Chen, Zi Chun Chia, Chun-Hua Hung, Wu-Chou Su and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 88 citations in OpenAlex.

  1. Article
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  6. Development of AuACS applied materials & interfaces · 2026
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  17. The Mutual Regulatory Role of Ferroptosis and Immunotherapy in Anti-tumor Therapy.Apoptosis : an international journal on programmed cell death · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Yu-Cheng ChinDepartment of Photonics, National Cheng Kung University, Tainan, 70101, Taiwan.
Li-Xing YangDepartment of Photonics, National Cheng Kung University, Tainan, 70101, Taiwan.
Fei-Ting HsuDepartment of Biological Science and Technology, China Medical University, Taichung, 406, Taiwan. sakiro920@mail.cmu.edu.tw.
Che-Wei HsuDivision of Urology, Department of Surgery, Taipei City Hospital Zhongxing Branch, Taipei, 103, Taiwan.
Te-Wei ChangDivision of Urology, Department of Surgery, Taipei City Hospital Heping Fuyou Branch, Taipei, 100, Taiwan.
Hsi-Ying ChenDepartment of Applied Chemistry, National Pingtung University, Pingtung, 900, Taiwan.
Linda Yen-Chien ChenNanofabrication Laboratory, Department of Electrical and Computer Engineering, University of Canterbury, Christchurch, New Zealand.
Zi Chun ChiaDepartment of Photonics, National Cheng Kung University, Tainan, 70101, Taiwan.
Chun-Hua HungCenter of Applied Nanomedicine, National Cheng Kung University, Tainan, 70101, Taiwan.
Wu-Chou SuCenter of Applied Nanomedicine, National Cheng Kung University, Tainan, 70101, Taiwan.
Yi-Chun ChiuDivision of Urology, Department of Surgery, Taipei City Hospital Heping Fuyou Branch, Taipei, 100, Taiwan. DAM15@tpech.gov.tw.
Chih-Chia HuangDepartment of Photonics, National Cheng Kung University, Tainan, 70101, Taiwan. c2huang@email.ncku.edu.tw.
Mei-Yi LiaoDepartment of Applied Chemistry, National Pingtung University, Pingtung, 900, Taiwan. myliao@mail.nptu.edu.tw.
National Cheng Kung University · TWTaipei City Hospital · TWNational Pingtung University · TWChina Medical University · TWUniversity of Canterbury · NZ

Funding

Ministry of Science and Technology, Taiwan MOST 108-2113-M-006-012-MY3Ministry of Science and Technology, Taiwan MOST 110-2113-M-153-001Ministry of Science and Technology, Taiwan MOST 110-2221-E-532 -001Taipei City Hospital (TCH) and the Department of Health, Taipei City Government TCH No. 11001-62-004
6 · The paper itself

Abstract

The escape of bladder cancer from immunosurveillance causes monotherapy to exhibit poor efficacy; therefore, designing a multifunctional nanoparticle that boosts programmed cell death and immunoactivation has potential as a treatment strategy. Herein, we developed a facile one-pot coprecipitation reaction to fabricate cluster-structured nanoparticles (CNPs) assembled from Fe

Indexed as

FerroptosisNanoparticlesNeoplasmsPhotochemotherapyUrinary Bladder NeoplasmsCD8-Positive T-LymphocytesCell Line, TumorChlorophyllFerric CompoundsHumansImmunizationImmunotherapyIronPhotosensitizing AgentsReactive Oxygen SpeciesTumor MicroenvironmentChlorophyllFerric Compoundsferric oxideIronPhotosensitizing AgentsReactive Oxygen Species

Identifiers

PMID35953837
PMCPMC9367122
OpenAlexW4291020686

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.