Evidence map›Paper›PMID 35953649›Full record

ReviewNature biomedical engineering2022

Self-supervised learning in medicine and healthcare.

Rayan Krishnan, Pranav Rajpurkar, Eric J Topol

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature biomedical engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 209 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
209citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

209 citing papers in PubMed, 1 synthesis or guideline pooled it.

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149 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rayan KrishnanDepartment of Computer Science, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-3481-020X
Pranav Rajpurkar *Department of Biomedical Informatics, Harvard University, Boston, MA, USA. pranav_rajpurkar@hms.harvard.edu.ORCID http://orcid.org/0000-0002-8030-3727
Eric J Topol *Scripps Research Translational Institute, Scripps Research, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-1478-4729

Funding

Scripps Translational Science InstituteUL1TR002550 · NCATS · SCRIPPS RESEARCH INSTITUTE, THE · PI TOPOL, ERIC JEFFREY · 2018 to 2022
$28.9M
U.S. Department of Health & Human Services | National Institutes of Health (NIH) UL1TR002550
6 · The paper itself

Abstract

The development of medical applications of machine learning has required manual annotation of data, often by medical experts. Yet, the availability of large-scale unannotated data provides opportunities for the development of better machine-learning models. In this Review, we highlight self-supervised methods and models for use in medicine and healthcare, and discuss the advantages and limitations of their application to tasks involving electronic health records and datasets of medical images, bioelectrical signals, and sequences and structures of genes and proteins. We also discuss promising applications of self-supervised learning for the development of models leveraging multimodal datasets, and the challenges in collecting unbiased data for their training. Self-supervised learning may accelerate the development of medical artificial intelligence.

Indexed as

Artificial IntelligenceMedicineDelivery of Health CareMachine LearningSupervised Machine Learning

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.