Evidence map›Paper›PMID 35953484›Full record

ArticleNature communications2022

SARS-CoV-2 and other respiratory pathogens are detected in continuous air samples from congregate settings.

Mitchell D Ramuta, Christina M Newman, Savannah F Brakefield, Miranda R Stauss, Roger W Wiseman, Amanda Kita-Yarbro, Eli J O'Connor, Neeti Dahal, Ailam Lim, Keith P Poulsen and 18 more

Abstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Shotgun metagenomics on indoor air for surveillance of respiratory, enteric, and skin viruses in a Belgian daycare setting, January to December 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Article
  18. Identifying changes in viral fitness using population genetic structure.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

28 authors.

Mitchell D RamutaDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0003-2134-610X
Christina M NewmanDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, USA.
Savannah F BrakefieldDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, USA.
Miranda R StaussWisconsin National Primate Research Center, Madison, WI, USA.
Roger W WisemanDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, USA.
Amanda Kita-YarbroPublic Health Madison & Dane County, Madison, WI, USA.
Eli J O'ConnorEAGLE School, Fitchburg, WI, USA.
Neeti DahalWisconsin Veterinary Diagnostic Laboratory, Madison, WI, USA.
Ailam LimWisconsin Veterinary Diagnostic Laboratory, Madison, WI, USA.
Keith P PoulsenWisconsin Veterinary Diagnostic Laboratory, Madison, WI, USA.
Nasia SafdarUniversity of Wisconsin Hospitals and Clinics, Madison, WI, USA.
John A MarxUniversity of Wisconsin Hospitals and Clinics, Madison, WI, USA.
Molly A AccolaUniversity of Wisconsin Hospitals and Clinics, Madison, WI, USA.
William M RehrauerDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, USA.
Julia A ZimmerCity of Milwaukee Health Department Laboratory, Milwaukee, WI, USA.ORCID 0000-0002-2507-2700
Manjeet KhubbarCity of Milwaukee Health Department Laboratory, Milwaukee, WI, USA.
Lucas J BeversdorfCity of Milwaukee Health Department Laboratory, Milwaukee, WI, USA.
Emma C BoehmDepartment of Veterinary and Biomedical Sciences, University of Minnesota, Twin Cities, Minneapolis, MN, USA.
David CastañedaDepartment of Veterinary and Biomedical Sciences, University of Minnesota, Twin Cities, Minneapolis, MN, USA.
Clayton RushfordDepartment of Molecular Microbiology and Immunology, University of Missouri, School of Medicine, Columbia, MO, USA.
Devon A GregoryDepartment of Molecular Microbiology and Immunology, University of Missouri, School of Medicine, Columbia, MO, USA.
Joseph D YaoDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-5988-8927
Sanjib BhattacharyyaCity of Milwaukee Health Department Laboratory, Milwaukee, WI, USA.
Marc C JohnsonDepartment of Molecular Microbiology and Immunology, University of Missouri, School of Medicine, Columbia, MO, USA.
Matthew T AliotaDepartment of Veterinary and Biomedical Sciences, University of Minnesota, Twin Cities, Minneapolis, MN, USA.ORCID 0000-0002-6902-9149
Thomas C FriedrichDepartment of Pathobiological Sciences, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0001-9831-6895
David H O'Connor *Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0003-2139-470X
Shelby L O'Connor *Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, USA. slfeinberg@wisc.edu.ORCID 0000-0003-0183-5010

Funding

WNPRC Supplemental Request for Nonhuman Primate Enclosures to Equip HIV/AIDS-Related Research FacilitiesP51OD011106 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Dorota A. Grejner-Brzezinska · 2012 to 2026
$150.7M
Microbial Pathogenesis &Host Responses Training ProgramT32AI055397 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI KLEIN, BRUCE STEVEN · 2003 to 2024
$5.5M
Wastewater Detection of COVID-19U01DA053893 · NIDA · MISSOURI STATE DEPT/ HEALTH & SENIOR SRV · PI WENZEL, JEFF · 2021 to 2022
$4.0M
NIAID NIH HHS T32 AI055397NIDA NIH HHS U01 DA053893NIH HHS P51 OD011106
6 · The paper itself

Abstract

Two years after the emergence of SARS-CoV-2, there is still a need for better ways to assess the risk of transmission in congregate spaces. We deployed active air samplers to monitor the presence of SARS-CoV-2 in real-world settings across communities in the Upper Midwestern states of Wisconsin and Minnesota. Over 29 weeks, we collected 527 air samples from 15 congregate settings. We detected 106 samples that were positive for SARS-CoV-2 viral RNA, demonstrating that SARS-CoV-2 can be detected in continuous air samples collected from a variety of real-world settings. We expanded the utility of air surveillance to test for 40 other respiratory pathogens. Surveillance data revealed differences in timing and location of SARS-CoV-2 and influenza A virus detection. In addition, we obtained SARS-CoV-2 genome sequences from air samples to identify variant lineages. Collectively, this shows air sampling is a scalable, high throughput surveillance tool that could be used in conjunction with other methods for detecting respiratory pathogens in congregate settings.

Indexed as

COVID-19SARS-CoV-2HumansMinnesotaRNA, ViralWisconsinRNA, Viral

Identifiers

PMID35953484
PMCPMC9366802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.