Evidence map›Paper›PMID 35953248›Full record

ArticleBMJ open2022

Children in the household and risk of severe COVID-19 during the first three waves of the pandemic: a prospective registry-based cohort study of 1.5 million Swedish men.

Agnes Af Geijerstam, Kirsten Mehlig, Monica Hunsberger, Maria Åberg, Lauren Lissner

Erratum issuedAbstract read
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Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Agnes Af GeijerstamSchool of Public Health and Community Medicine, University of Gothenburg Institute of Medicine, Goteborg, Sweden agnes.af.geijerstam@gu.se.ORCID http://orcid.org/0000-0002-0897-6548
Kirsten MehligSchool of Public Health and Community Medicine, University of Gothenburg Institute of Medicine, Goteborg, Sweden.
Monica HunsbergerSchool of Public Health and Community Medicine, University of Gothenburg Institute of Medicine, Goteborg, Sweden.
Maria ÅbergSchool of Public Health and Community Medicine, University of Gothenburg Institute of Medicine, Goteborg, Sweden.
Lauren LissnerSchool of Public Health and Community Medicine, University of Gothenburg Institute of Medicine, Goteborg, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate whether Swedish men living with children had elevated risk for severe COVID-19 or infection with SARS-CoV-2 during the first three waves of the pandemic.

designProspective registry-based cohort study.

participants1 557 061 Swedish men undergoing military conscription between 1968 and 2005 at a mean age of 18.3 (SD 0.73) years.

main outcome measuresInfection with SARS-CoV-2 and hospitalisation due to COVID-19 from March 2020 to September 2021.

resultsThere was a protective association between preschool children at home and hospitalisation due to COVID-19 during the first and third waves compared with only older or no children at all, with ORs (95% CIs) 0.63 (0.46 to 0.88) and 0.75 (0.68 to 0.94) respectively. No association was observed for living with children 6-12 years old, but for 13-17 years old, the risk increased. Age in 2020 did not explain these associations. Further adjustment for socioeconomic and health factors did not attenuate the results. Exposure to preschool children also had a protective association with testing positive with SARS-CoV-2, with or without hospitalisation, OR=0.91 (95% CI 0.89 to 0.93), while living with children of other ages was associated with increased odds of infection.

conclusionsCohabiting with preschool children was associated with reduced risk for severe COVID-19. Living with school-age children between 6 and 12 years had no association with severe COVID-19, but sharing the household with teenagers and young adults was associated with elevated risk. Our results are of special interest since preschools and compulsory schools (age 6-15 years) in Sweden did not close in 2020.

Indexed as

COVID-19PandemicsAdolescentChildChild, PreschoolCohort StudiesHumansMaleRegistriesSARS-CoV-2SwedenYoung AdultCOVID-19EpidemiologyEPIDEMIOLOGY

Identifiers

PMID35953248
PMCPMC9378946

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.