Evidence map›Paper›PMID 35953239›Full record

ArticleRMD open2022

Distribution patterns of arterial affection and the influence of glucocorticoids on

Leander Malich, Falk Gühne, Tobias Hoffmann, Ansgar Malich, Tobias Weise, Peter Oelzner, Gunter Wolf, Martin Freesmeyer, Alexander Pfeil

Open access · goldAbstract read
In one paragraph

Article in RMD open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Comparing Diagnostic Performance of Short and Long [Diagnostics (Basel, Switzerland) · 2023
    Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Leander MalichDepartment of Internal Medicine III, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany.
Falk GühneClinic of Nuclear Medicine, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany.
Tobias HoffmannDepartment of Internal Medicine III, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany.ORCID 0000-0003-2959-1126
Ansgar MalichInstitute of Diagnostic Radiology, Suedharz-Hospital Nordhausen, Nordhausen, Germany.
Tobias WeiseBiocontrol Jena, Jena, Germany.
Peter OelznerDepartment of Internal Medicine III, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany.
Gunter WolfDepartment of Internal Medicine III, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany.
Martin Freesmeyer *Clinic of Nuclear Medicine, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany.
Alexander Pfeil *Department of Internal Medicine III, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany alexander.pfeil@med.uni-jena.de.ORCID 0000-0002-2709-6685
Jena University Hospital · DEJena Bioscience (Germany) · DESüdharz Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGiant cell arteritis (GCA) with the involvement of extracranial vessels is increasingly coming into focus. Isolated aortic involvement in the acute phase of GCA is probably more frequent than estimated because only a minority of patients show typical symptoms.

methodsThe study included 60 patients with GCA at the onset of a GCA. All patients had undergone a PET/CT scan. 44 patients were GC naïve and 16 patients received GC.

resultsThe most affected arteries were the ascending aorta (72%), followed by the brachiocephalic trunk (62%), aortic arch (60%) and descending aorta (60%). The aorta and its branches showed an inflammatory involvement in 83.3% of patients. A singular affection of the aorta and the brachiocephalic trunk was revealed in 20% of cases. GC-naïve patients (95.5%) had more frequently affected arteries compared with GC-treated patients (50%).

conclusionOur study showed the frequent involvement of the thoracic aorta and brachiocephalic trunk in patients with GCA using PET/CT. Since these vascular compartments cannot be visualised by ultrasound, we advocate screening imaging of the aorta with PET/CT when GCA is suspected. Because the use of GC is associated with a marked decrease in the inflamed vascular segment in GCA, PET/CT should be performed as soon as possible.

Indexed as

Giant Cell ArteritisArteriesFluorodeoxyglucose F18GlucocorticoidsHumansPositron-Emission TomographyPositron Emission Tomography Computed TomographyRetrospective StudiesFluorodeoxyglucose F18Glucocorticoidsgiant cell arteritisglucocorticoidsinflammation

Identifiers

PMID35953239
PMCPMC9379531
OpenAlexW4293901182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.