Evidence map›Paper›PMID 35952715›Full record

ArticleCancer research and treatment2023

Epidemiologic and Clinical Outcomes of Pediatric Renal Tumors in Korea: A Retrospective Analysis of The Korean Pediatric Hematology and Oncology Group (KPHOG) Data.

Kyung-Nam Koh, Jung Woo Han, Hyoung Soo Choi, Hyoung Jin Kang, Ji Won Lee, Keon Hee Yoo, Ki Woong Sung, Hong Hoe Koo, Kyung Taek Hong, Jung Yoon Choi and 39 more

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PubMed Full text at PMC Publisher
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Article in Cancer research and treatment, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

49 authors at 20 institutions in 2 countries.

Kyung-Nam KohDivision of Pediatric Hematology/Oncology, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Korea.
Jung Woo HanDivision of Pediatric Hematology and Oncology, Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
Hyoung Soo ChoiDepartment of Pediatrics, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Hyoung Jin KangDepartment of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.
Ji Won LeeDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Keon Hee YooDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Ki Woong SungDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Hong Hoe KooDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Kyung Taek HongDepartment of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.
Jung Yoon ChoiDepartment of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.
Sung Han KangDivision of Pediatric Hematology/Oncology, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Korea.
Hyery KimDivision of Pediatric Hematology/Oncology, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Korea.
Ho Joon ImDivision of Pediatric Hematology/Oncology, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Korea.
Seung Min HahnDivision of Pediatric Hematology and Oncology, Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
Chuhl Joo LyuDivision of Pediatric Hematology and Oncology, Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
Hee-Jo BaekDepartment of Pediatrics, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Gwangju, Korea.
Hoon KookDepartment of Pediatrics, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Gwangju, Korea.
Kyung Mi ParkDepartment of Pediatrics, Pusan National University School of Medicine, Yangsan, Korea.
Eu Jeen YangDepartment of Pediatrics, Pusan National University School of Medicine, Yangsan, Korea.
Young Tak LimDepartment of Pediatrics, Pusan National University School of Medicine, Yangsan, Korea.
Seongkoo KimDepartment of Pediatrics, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Jae Wook LeeDepartment of Pediatrics, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Nack-Gyun ChungDepartment of Pediatrics, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Bin ChoDepartment of Pediatrics, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Meerim ParkCenter for Pediatric Cancer, Department of Pediatrics, National Cancer Center, Goyang, Korea.
Hyeon Jin ParkCenter for Pediatric Cancer, Department of Pediatrics, National Cancer Center, Goyang, Korea.
Byung-Kiu ParkCenter for Pediatric Cancer, Department of Pediatrics, National Cancer Center, Goyang, Korea.
Jun Ah LeeDepartment of Pediatrics, Korea Cancer Center Hospital, Seoul, Korea.
Jun Eun ParkDepartments of Pediatrics, Korea University College of Medicine, Seoul, Korea.
Soon Ki KimDepartment of Pediatrics, College of Medicine, Inha University Hospital, Incheon, Korea.
Ji Yoon KimDepartment of Pediatrics, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu, Korea.
Hyo Sun KimDepartment of Pediatrics, Inje University Haeundae Paik Hospital, Busan, Korea.
Youngeun MaDepartment of Pediatrics, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Kyung Duk ParkDepartment of Pediatrics and Research Institute of Clinical Medicine of Jeonbuk National University-Jeonbuk National University Hospital, Jeonbuk National University Medical School, Jeonju, Korea.
Sang Kyu ParkDepartment of Pediatrics, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.
Eun Sil ParkDepartment of Pediatrics, Gyeongsang National University School of Medicine, Jinju, Korea.
Ye Jee ShimDepartment of Pediatrics, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Korea.
Eun Sun YooDepartment of Pediatrics, Ewha Womans University Seoul Hospital, Ewha Womans University College of Medicine, Seoul, Korea.
Kyung Ha RyuDepartment of Pediatrics, Ewha Womans University Seoul Hospital, Ewha Womans University College of Medicine, Seoul, Korea.
Jae Won YooDepartment of Pediatrics, Chungnam National University College of Medicine, Daejeon, Korea.
Yeon Jung LimDepartment of Pediatrics, Chungnam National University College of Medicine, Daejeon, Korea.
Hoi Soo YoonDepartment of Pediatrics, Kyung Hee University College of Medicine, Seoul, Korea.
Mee Jeong LeeDepartment of Pediatrics, Dankook University College of Medicine, Cheonan, Korea.
Jae Min LeeDepartment of Pediatrics, Yeungnam University College of Medicine, Daegu, Korea.
In-Sang JeonDepartment of Pediatrics, Gachon University Gil Medical Center, Incheon, Korea.
Hye Lim JungDepartment of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
Hee Won ChuehDepartment of Pediatrics, Dong-A University College of Medicine, Busan, Korea.
Seunghyun WonMedical Research Collaborating Center, Seoul National University Bundang Hospital, Seongnam, Korea.
Korean Pediatric Hematology and Oncology Group (KPHOG)
Chungnam National University · KRNational Cancer Center · USSamsung Medical Center · KRSeoul National University · KRSeoul National University Bundang Hospital · KRSungkyunkwan University · KRYonsei University · KRAsan Medical Center · KRCatholic University of Korea · KRChonnam National University Hospital · KREwha Womans University · KRInha University Hospital · KRPusan National University · KRThe Catholic University of Korea Seoul St. Mary's Hospital · KRUlsan College · KRDankook University · KRDong-A University · KRGachon University Gil Medical Center · KRGyeongsang National University · KRJeonbuk National University Hospital · KR

Funding

Korean Pediatric Hematology and Oncology Groupthe Korean Society of Pediatric Hematology-Oncology
6 · The paper itself

Abstract

purposeRenal tumors account for approximately 7% of all childhood cancers. These include Wilms tumor (WT), clear cell sarcoma of the kidney (CCSK), malignant rhabdoid tumor of the kidney (MRTK), renal cell carcinoma (RCC), congenital mesoblastic nephroma (CMN) and other rare tumors. We investigated the epidemiology of pediatric renal tumors in Korea. MATERIALS AND

methodsFrom January 2001 to December 2015, data of pediatric patients (0-18 years) newly-diagnosed with renal tumors at 26 hospitals were retrospectively analyzed.

resultsAmong 439 patients (male, 240), the most common tumor was WT (n=342, 77.9%), followed by RCC (n=36, 8.2%), CCSK (n=24, 5.5%), MRTK (n=16, 3.6%), CMN (n=12, 2.7%), and others (n=9, 2.1%). Median age at diagnosis was 27.1 months (range 0-225.5) and median follow-up duration was 88.5 months (range 0-211.6). Overall, 32 patients died, of whom 17, 11, 1, and 3 died of relapse, progressive disease, second malignant neoplasm, and treatment-related mortality. Five-year overall survival and event free survival were 97.2% and 84.8% in WT, 90.6% and 82.1% in RCC, 81.1% and 63.6% in CCSK, 60.3% and 56.2% in MRTK, and 100% and 91.7% in CMN, respectively (p < 0.001).

conclusionThe pediatric renal tumor types in Korea are similar to those previously reported in other countries. WT accounted for a large proportion and survival was excellent. Non-Wilms renal tumors included a variety of tumors and showed inferior outcome, especially MRTK. Further efforts are necessary to optimize the treatment and analyze the genetic characteristics of pediatric renal tumors in Korea.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsNephroma, MesoblasticRhabdoid TumorSarcomaWilms TumorChildHumansMaleNeoplasm Recurrence, LocalRepublic of KoreaRetrospective StudiesChildEpidemiologyRenal tumors

Identifiers

PMID35952715
PMCPMC9873342
OpenAlexW4290991856

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