ArticlePloS one2022
The time to initiate trophic feeding and its predictors among preterm neonate admitted to neonatal intensive care unit, Multicenter study, Northwest Ethiopia.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 12 citations in OpenAlex.
- Reducing unnecessary antibiotic exposure among neonates evaluated for suspected early-onset sepsis through an adapted risk-stratification and antimicrobial stewardship pathway in northwest Ethiopia: a prospective quality improvement study.BMJ paediatrics open · 2026Article
- Time to initiate trophic feeding and predictors among preterm neonates admitted at General Hospitals in Tigray, 2025.PloS one · 2026Article
- How long does it take to start minimal enteral feeding in preterm Neonates admitted to NICUs in Southern Oromia, Ethiopia?Italian journal of pediatrics · 2025Observational
- Trophic feeding initiation and its predictors in preterm neonates admitted to Neonatal Intensive Care Units: Multicenter study, Addis Ababa.SAGE open medicine · 2025Article
- Factors influencing late antenatal care of Muslim pregnant women: A predictive correlational study in Aceh, Indonesia.Belitung nursing journal · 2024Article
- Inadequate weight gain and factors influencing it among preterm neonates in neonatal intensive care units in the Amhara region, Ethiopia, in 2022.Frontiers in pediatrics · 2024Article
- Experiences of Indonesian nurses in improving preterm oral feeding readiness in special care units: A qualitative descriptive study.Belitung nursing journal · 2023Article
- Time to Initiate Trophic Feeding and Its Predictors Among Preterm Infants at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia.Sage open pediatricsArticle
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTrophic feeding is a small volume, hypo-caloric feeding, gut priming or minimal enteral feeding acclimate the immature gut of enteral fasting preterm neonates. Delayed starting of trophic feeding had resulted in short and long-term physical and neurological sequels. The current study aimed to estimate the time to initiate trophic feeding and its predictors among preterm neonates admitted in the neonatal intensive care unit of Debre Markos, Felege Hiwot, and Tibebe Ghion comprehensive specialized hospitals.
methodsAn institutional-based prospective follow-up study was conducted among 210 neonates. The data were collected with interview and chart review, entered into Epi data 3.1 and exported to Stata 14.1 for analysis. Multivariable Cox regression models were fitted to identify predictors of time to initiate trophic feeding.
resultA total of 210 neonates were followed for 10136 person-hours of risk time and 191 (90.95%) of neonates were started trophic feeding. The overall incidence of starting trophic feeding was 2 per 100 (95% CI: 2, 2.2) person-hours observations. The median survival time was 42 hours (95% CI: 36, 48). APGAR- score at first minute <7 (AHR: 0.6, 95% CI: 0.44, 0.82), gestational age of <34 weeks (AHR: 0.69, 95% CI: 0.5, 0.94), presence of respiratory distress syndrome (AHR: 0.5, 95% CI: 0.36, 0.68), presence of hemodynamic instability (AHR: 0.37, 95% CI: 0.24, 0.57), presence of perinatal asphyxia (AHR: 0.63, 95% CI: 0.44, 0.89), cesarean section delivery (AHR: 0.63, 95% CI: 0.44, 89) and being delivered within the study hospitals (AHR: 0.54, 95% CI: 0.39, 0.74) were found to be statistically significant predictors of time to initiate trophic feeding.
conclusionThere was a significant delay to initiate trophic feeding in the studied hospitals. Gestational age of below 34 weeks, APGAR-score of less than seven, out-born delivery, cesarean delivery, presence of respiratory distress syndrome; perinatal asphyxia, and hemodynamic instability were predictors of delay in starting of trophic feeding. Standardized feeding guideline has to be implemented to overcome delays in enteral feeding initiation.
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