Evidence map›Paper›PMID 35951511›Full record

ArticlePloS one2022

SARS-CoV-2 reliably detected in frozen saliva samples stored up to one year.

Jennifer K Frediani, Kaleb B McLendon, Adrianna Westbrook, Scott E Gillespie, Anna Wood, Tyler J Baugh, William O'Sick, John D Roback, Wilbur A Lam, Joshua M Levy

Abstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jennifer K FredianiNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, United States of America.ORCID 0000-0002-4634-0591
Kaleb B McLendonThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies, Atlanta, GA, United States of America.
Adrianna WestbrookThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies, Atlanta, GA, United States of America.ORCID 0000-0001-9309-6205
Scott E GillespieDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States of America.ORCID 0000-0003-1295-3602
Anna WoodDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States of America.
Tyler J BaughThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies, Atlanta, GA, United States of America.
William O'SickThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies, Atlanta, GA, United States of America.
John D RobackThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies, Atlanta, GA, United States of America.
Wilbur A LamThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies, Atlanta, GA, United States of America.
Joshua M LevyThe Atlanta Center for Microsystems-Engineered Point-of-Care Technologies, Atlanta, GA, United States of America.

Funding

Technology Training and Dissemination CoreU54EB027690 · NIBIB · EMORY UNIVERSITY · PI Wilbur A Lam, GREGORY S MARTIN · 2018 to 2026
$96.1M
Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
NCATS NIH HHS UL1 TR002378NIBIB NIH HHS U54 EB027690
6 · The paper itself

Abstract

Viability of saliva samples stored for longer than 28 days has not been reported in the literature. The COVID-19 pandemic has spawned new research evaluating various sample types, thus large biobanks have been started. Residual saliva samples from university student surveillance testing were retested on SalivaDirect and compared with original RT-PCR (cycle threshold values) and quantitative antigen values for each month in storage. We conclude that saliva samples stored at -80°C are still viable in detecting SARS-CoV-2 after 12 months of storage, establishing the validity of these samples for future testing.

Indexed as

COVID-19SARS-CoV-2COVID-19 TestingHumansPandemicsRNA, ViralSalivaSpecimen HandlingRNA, Viral

Identifiers

PMID35951511
PMCPMC9371282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.