Evidence map›Paper›PMID 35951480›Full record

ArticleJournal of feline medicine and surgery2022

Prevalence of polycystic kidney disease in Persian and Persian-related cats in western Mexico.

Néstor G Michel-Regalado, Miguel A Ayala-Valdovinos, Jorge Galindo-García, Theodor Duifhuis-Rivera, Abraham Virgen-Méndez

Abstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Néstor G Michel-RegaladoDepartment of Animal Production, Veterinary Science Division, University Center of Biological and Agricultural Sciences, University of Guadalajara, Zapopan, México.ORCID 0000-0001-5809-4204
Miguel A Ayala-ValdovinosDepartment of Animal Production, Veterinary Science Division, University Center of Biological and Agricultural Sciences, University of Guadalajara, Zapopan, México.ORCID 0000-0002-7535-2452
Jorge Galindo-GarcíaDepartment of Animal Production, Veterinary Science Division, University Center of Biological and Agricultural Sciences, University of Guadalajara, Zapopan, México.ORCID 0000-0001-8951-9471
Theodor Duifhuis-RiveraDepartment of Animal Production, Veterinary Science Division, University Center of Biological and Agricultural Sciences, University of Guadalajara, Zapopan, México.ORCID 0000-0002-8748-2481
Abraham Virgen-MéndezDepartment of Animal Production, Veterinary Science Division, University Center of Biological and Agricultural Sciences, University of Guadalajara, Zapopan, México.ORCID 0000-0001-5787-2561

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAutosomal dominant polycystic kidney disease (ADPKD), the most frequently diagnosed hereditary disease affecting Persian cats, is caused by a cytosine-to-adenine transversion (10063C>A) in

methodsBlood samples were collected from 104 cats (89 Persian, seven Persian crossbreed, five Siamese and three Himalayan cats). Genotyping was performed with our proposed PCR restriction fragment length polymorphism (RFLP) assay, as well as a previously established PCR-RFLP method for validation. The genotypes of control cats were corroborated by a commercial veterinary genetics laboratory.

resultsOur proposed PCR-RFLP assay and the validated PCR-RFLP methodology indicated that 24/104 (23.1%) cats in this study were heterozygous carriers of the 10063C>A SNP, including 23/89 Persian cats (25.8%) and 1/7 Persian crossbreed cats (14.3%). No Siamese or Himalayan cats were carriers. There were no discrepancies between the results obtained with our proposed assay and those obtained with the validation method or with commercial laboratory results. CONCLUSIONS AND RELEVANCE: The carrier frequency of the

Indexed as

Cat DiseasesPolycystic Kidney DiseasesAnimalsCatsgenotypingPCR-RFLPPersianPKD1

Identifiers

PMID35951480
PMCPMC10812362

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.