Evidence map›Paper›PMID 35951211›Full record

ArticleMolecular imaging and biology2023

Radiosynthesis and Evaluation of a C-11 Radiotracer for Transient Receptor Potential Canonical 5 in the Brain.

Yanbo Yu, Hao Jiang, Qianwa Liang, Lin Qiu, Tianyu Huang, Hongzhen Hu, Vadim Y Bolshakov, Joel S Perlmutter, Zhude Tu

Open access · greenAbstract read
In one paragraph

Article in Molecular imaging and biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Development and Optimization ofACS pharmacology & translational science · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yanbo YuDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.ORCID 0000-0002-6687-9850
Hao JiangDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Qianwa LiangDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Lin QiuDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Tianyu HuangDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Hongzhen HuCenter for the Study of Itch and Sensory Disorders, Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Vadim Y BolshakovDepartment of Psychiatry, McLean Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Joel S PerlmutterDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Zhude TuDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA. zhudetu@wustl.edu.ORCID 0000-0003-0325-835X
Washington University in St. Louis · USHarvard University · US

Funding

INVESTIGATIONS OF DEMENTIA IN PARKINSON DISEASER01NS075321 · NINDS · WASHINGTON UNIVERSITY · PI CAMPBELL, MEGHAN C, PERLMUTTER, JOEL SYNES · 2011 to 2021
$8.2M
PET SPHINGOSINE-1-PHOSPHATE RECEPTOR 1 (S1PR1) RADIOTRACERS FOR MULTIPLE SCLEROSISR01NS103988 · NINDS · WASHINGTON UNIVERSITY · PI Tammie Lee Smith Benzinger, Zhude Tu · 2017 to 2026
$5.3M
PET PROBES FOR IMAGING THE VESICULAR ACETYLCHOLINE TRANSPORTERR01NS075527 · NINDS · WASHINGTON UNIVERSITY · PI TU, ZHUDE · 2011 to 2021
$4.9M
Neuroinflammatory Biomarkers for Nigrostriatal InjuryR01NS107281 · NINDS · WASHINGTON UNIVERSITY · PI PERLMUTTER, JOEL SYNES · 2019 to 2023
$3.3M
Neuroimaging of PDE10AR01NS103957 · NINDS · WASHINGTON UNIVERSITY · PI PERLMUTTER, JOEL SYNES, TU, ZHUDE · 2017 to 2021
$3.1M
NINDS NIH HHS R01 NS075321NINDS NIH HHS R01 NS075527NINDS NIH HHS R01 NS103957NINDS NIH HHS R01 NS103988NINDS NIH HHS R01 NS107281
6 · The paper itself

Abstract

purposeTRPC5 belongs to the mammalian superfamily of transient receptor potential (TRP) Ca PROCEDURES: [

results[

conclusionsOur data showed that [

Indexed as

BrainPositron-Emission TomographyAnimalsCarbon RadioisotopesHumansMaleMammalsMiceMice, KnockoutPrimatesRadiopharmaceuticalsRatsRats, Sprague-DawleyTissue DistributionTRPC Cation ChannelsCarbon-11Carbon RadioisotopesRadiopharmaceuticalsTrpc5 protein, mouseTrpc5 protein, ratTRPC Cation ChannelsCarbon-11 RadiotracerIonic ChannelPET ImagingTRPC 5

Identifiers

PMID35951211
PMCPMC9918595
OpenAlexW4290802290

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.