Evidence map›Paper›PMID 35950698›Full record

ArticleJournal of addictive diseases

Detoxification, 12-step meeting attendance, and non-fatal opioid overdoses among a suburban/exurban population with opioid use disorder.

Sarah E Clingan, Susan I Woodruff, Tommi L Gaines, Peter J Davidson

Open access · greenAbstract read
In one paragraph

Article in Journal of addictive diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Sarah E ClinganDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA, USA.ORCID 0000-0002-2714-2039
Susan I WoodruffSchool of Social Work, San Diego State University, San Diego, CA, USA.
Tommi L GainesDivision of Infectious Diseases and Global Public Health, Department of Medicine, University of California, San Diego, CA, USA.
Peter J DavidsonDivision of Infectious Diseases and Global Public Health, Department of Medicine, University of California, San Diego, CA, USA.
University of California San Diego · USSan Diego State University · USUniversity of California, Los Angeles · US

Funding

UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Maile Ann Young Karris · 1994 to 2026
$78.4M
Impacts of a Novel law-enforcement delivered intervention on drug user healthR01DA040648 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DAVIDSON, PETER JOHN · 2016 to 2021
$2.6M
OPR mis/use and transitions to heroin and injecting in suburban and exurban Southern CaliforniaU01CE002778 · CE · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DAVIDSON, PETER JOHN · 2016 to 2017
$600k
NCATS NIH HHS UL1 TR001442NCIPC CDC HHS U01 CE002778NIAID NIH HHS P30 AI036214NIDA NIH HHS R01 DA040648
6 · The paper itself

Abstract

backgroundDrug overdoses are the leading cause of injury death in the United States with an estimated 105,752 individuals dying from an overdose in the United States in a 12-month period ending October 2021. Given that people who have opioid use disorder (OUD) are at an increased risk of death, it is crucial to assess risk factors associated with opioid overdose to improve interventions.

objectivesWe examine factors associated with non-fatal overdose among a suburban/exurban population with OUD in Southern California.

methodsParticipants were recruited by convenience sampling (n = 355) and were interviewed between November 2017 to August 2018. Participants were eligible for the study if they had a history of pharmaceutical opioid use.

resultsA total of 198 (55.8%) participants reported at least one overdose in their lifetime. A total of 229 participants identified as male, 124 identified as female, and 2 identified as non-binary. When controlling for demographic factors, non-oral opioid administration at first opioid use (AOR 2.82, 95% CI 1.52-5.22), having a history of methadone detoxification, (AOR 2.23, 95% CI 1.27-3.91), history of buprenorphine detoxification (AOR 1.77, 95% CI 1.02-3.07), and history of 12 step attendance (AOR 1.89, 95% CI 1.12-3.20) were found to be independently and positively associated with lifetime opioid overdose.

conclusionsDetoxification with buprenorphine and methadone was found to be associated with having a non-fatal opioid overdose. Buprenorphine and methadone should not be prescribed as a detoxification medication as long-term use of medication for OUD results in better outcomes than medication that is used short-term.

Indexed as

medication for opioid use disorderOpioid overdoserisk factors

Identifiers

PMID35950698
PMCPMC9918603
OpenAlexW4291020888

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.