Evidence map›Paper›PMID 35950657›Full record

ArticleComprehensive Physiology2022

The Role of B Lymphocyte Subsets in Adipose Tissue Development, Metabolism, and Aging.

Nicole C Fernandez, Kosaku Shinoda

Open access · greenAbstract read
In one paragraph

Article in Comprehensive Physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nicole C FernandezDepartment of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID http://orcid.org/0000-0003-2283-5837
Kosaku ShinodaDepartment of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID http://orcid.org/0000-0002-1928-0749
Albert Einstein College of Medicine · US

Funding

Training in Aging ResearchT32AG023475 · NIA · ALBERT EINSTEIN COL OF MED YESHIVA UNIV · PI NIR J BARZILAI, DEREK Major HUFFMAN · 2004 to 2026
$8.6M
Molecular Mechanism of Brown Adipose Tissue RegressionR01DK128839 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI FENG, DAORONG, PESSIN, JEFFREY E. · 2021 to 2024
$2.3M
NIA NIH HHS T32 AG023475NIDDK NIH HHS R01 DK128839
6 · The paper itself

Abstract

Adipose tissue contains resident B lymphocytes (B cells) with varying immune functions and mechanisms, depending on the adipose depot type and location. The heterogeneity of B cells and their functions affect the immunometabolism of the adipose tissue in aging and age-associated metabolic disorders. B cells exist in categorizations of subsets that have developmental or phenotypic differences with varying functionalities. Subsets can be categorized as either protective or pathogenic depending on their secretion profile or involvement in metabolic maintenance. In this article, we summarized recent finding on the B cell heterogeneity and discuss how we can utilize our current knowledge of adipose resident B lymphocytes for potential treatment for age-associated metabolic disorders. © 2022 American Physiological Society. Compr Physiol 12: 1-13, 2022.

Indexed as

B-Lymphocyte SubsetsMetabolic DiseasesAdipogenesisAdipose TissueAgingHumans

Identifiers

PMID35950657
PMCPMC12834391
OpenAlexW4291020966

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.