ArticleJournal of applied clinical medical physics2022
Dosimetric evaluation of respiratory gating on a 0.35-T magnetic resonance-guided radiotherapy linac.
Article in Journal of applied clinical medical physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed.
- Characterizing the motion management system accuracy on a 1.5T MR-Linac.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2025Article
- Workflow to detect exceeded dose constraints in pancreatic stereotactic body irradiation after intrafraction motion during magnetic resonance-guided adaptive radiotherapy using a deep learning-refined contour propagation tool.Physics and imaging in radiation oncology · 2025Article
- Development of in-house software to process real-time cine magnetic resonance images acquired during 1.5 T MR-guided radiation therapy.Scientific reports · 2025Article
- Enhanced analysis of gating latency in 0.35T MR-linac through innovative time synchronization of a motion phantom and plastic scintillation detector.Journal of applied clinical medical physics · 2025Article
- Commissioning of a motion management system for a 1.5T Elekta Unity MR-Linac: A single institution experience.Journal of applied clinical medical physics · 2025Article
- Analysis of sagittal plane cine magnetic resonance imaging for measurement of pancreatic tumor residual motion during breath hold and evaluation of gating margins used in radiotherapy treatment.Journal of applied clinical medical physics · 2025Article
- Recent technical advancements and clinical applications of MR-guided radiotherapy in lung cancer treatment.Frontiers in oncology · 2025Review
- A simulation study of MR-guided proton therapy system using iron-yoked superconducting open MRI: a conceptual study.Journal of radiation research · 2024Article
- Quality assurance of an established online adaptive radiotherapy program: patch and software upgrade.Frontiers in oncology · 2024Article
- Accuracy of deformable image registration-based intra-fraction motion management in Magnetic Resonance-guided radiotherapy.Physics and imaging in radiation oncology · 2023Article
- Dosimetric evaluation of respiratory gating on a 0.35-T magnetic resonance-guided radiotherapy linac.Journal of applied clinical medical physics · 2022Article
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5 authors.
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Abstract
purposeThe commercial 0.35-T magnetic resonance imaging (MRI)-guided radiotherapy vendor ViewRay recently introduced upgraded real-time imaging frame rates based on compressed sensing techniques. Furthermore, additional motion tracking algorithms were made available. Compressed sensing allows for increased image frame rates but may compromise image quality. To assess the impact of this upgrade on respiratory gating accuracy, we evaluated gated dose distributions pre- and post-upgrade using a motion phantom and radiochromic film.
methodsSeven motion waveforms (four artificial, two patient-derived free-breathing, and one breath-holding) were used to drive an MRI-compatible motion phantom. A treatment plan was developed to deliver a 3-cm diameter spherical dose distribution typical of a stereotactic body radiotherapy plan. Gating was performed using 4-frames per second (fps) imaging pre-upgrade on the "default" tracking algorithm and 8-fps post-upgrade using the "small mobile targets" (SMT) and "large deforming targets" (LDT) tracking algorithms. Radiochromic film was placed in a moving insert within the phantom to measure dose. The planned and delivered dose distributions were compared using the gamma index with 3%/3-mm criteria. Dose-area histograms were produced to calculate the dose to 95% (D95) of the sphere planning target volume (PTV) and two simulated gross tumor volumes formed by contracting the PTV by 3 and 5 mm, respectively.
resultsGamma pass rates ranged from 18% to 93% over the 21 combinations of breathing trace and gating conditions examined. D95 ranged from 206 to 514 cGy. On average, the LDT algorithm yielded lower gamma and D95 values than the default and SMT algorithms.
conclusionRespiratory gating at 8 fps with the new tracking algorithms provides similar gating performance to the original algorithm with 4 fps, although the LDT algorithm had lower accuracy for our non-deformable target. This indicates that the choice of deformable image registration algorithm should be chosen deliberately based on whether the target is rigid or deforming.
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