Evidence map›Paper›PMID 35950038›Full record

ArticleBJUI compass2022

Prognostic differences among Grade Group 4 subgroups in robotic-assisted radical prostatectomy.

Takeshi Sasaki, Shin Ebara, Tomoyuki Tatenuma, Yoshinori Ikehata, Akinori Nakayama, Daiki Kato, Masahiro Toide, Tatsuaki Yoneda, Kazushige Sakaguchi, Jun Teishima and 7 more

Open access · goldAbstract read
In one paragraph

Article in BJUI compass, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 10 institutions in 1 country.

Takeshi SasakiDepartment of Nephro-Urologic Surgery and Andrology Mie University Graduate School of Medicine Tsu Japan.ORCID https://orcid.org/0000-0002-2458-5686
Shin EbaraDepartment of Urology Hiroshima City Hiroshima Citizens Hospital Hiroshima Japan.
Tomoyuki TatenumaDepartment of Urology Yokohama City University Yokohama Japan.
Yoshinori IkehataDepartment of Urology University of Toyama Toyama Japan.
Akinori NakayamaDepartment of Urology Dokkyo Medical University Saitama Medical Center Koshigaya Japan.
Daiki KatoDepartment of Urology Gifu University Graduate School of Medicine Gifu Japan.
Masahiro ToideDepartment of Urology Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital Tokyo Japan.
Tatsuaki YonedaDepartment of Urology Seirei Hamamatsu General Hospital Hamamatsu Japan.
Kazushige SakaguchiDepartment of Urology Toranomon Hospital Tokyo Japan.
Jun TeishimaDepartment of Urology Kobe City Medical Center West Hospital Kobe Japan.ORCID https://orcid.org/0000-0001-8429-1607
Kazuhide MakiyamaDepartment of Urology Yokohama City University Yokohama Japan.
Hiroshi KitamuraDepartment of Urology University of Toyama Toyama Japan.
Kazutaka SaitoDepartment of Urology Dokkyo Medical University Saitama Medical Center Koshigaya Japan.
Takuya KoieDepartment of Urology Gifu University Graduate School of Medicine Gifu Japan.
Fumitaka KogaDepartment of Urology Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital Tokyo Japan.ORCID https://orcid.org/0000-0001-7888-0085
Shinji UrakamiDepartment of Urology Toranomon Hospital Tokyo Japan.
Takahiro InoueDepartment of Nephro-Urologic Surgery and Andrology Mie University Graduate School of Medicine Tsu Japan.
Dokkyo Medical University Saitama Medical Center · JPGifu University · JPMie University · JPTokyo Metropolitan Komagome Hospital · JPToranomon Hospital · JPUniversity of Toyama · JPYokohama City University · JPHiroshima City Asa Citizens Hospital · JPKobe City Medical Center West Hospital · JPSeirei Hamamatsu General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To investigate whether the International Society of Urological Pathology Grade Group 4 (GG 4) subgroups have different oncological outcomes in Japanese prostate cancer (PCa) patients undergoing robotic-assisted radical prostatectomy (RARP). Patients and Methods: We conducted a retrospective multicentre cohort study in PCa patients undergoing RARP at 10 institutions in Japan. Pre- and post-operative variables were collected from enrolled patients. We evaluated biochemical recurrence and clinical and pathological variables in the different GG 4 subgroups. Results: A total of 3195 patients were enrolled in the study. Among them, 298 patients with GG 4 tumours (pathological Gleason scores [GSs] of 3 + 5 [ Conclusions: For patients with localized PCa undergoing RARP, pathological GS 4 + 4 and GS 5 + 3 were significantly associated with worse BCRFS than pathological GS 3 + 5. Pathological GS 3 + 5 may be overrated in GG 4. This observation emphasizes that primary and secondary GS should be considered to accurately stratify the risk of BCR after RARP.

Indexed as

Gleason scoregrade groupprostate cancerradical prostatectomyrobotic‐assisted

Identifiers

PMID35950038
PMCPMC9349593
OpenAlexW4281675647

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.