Evidence map›Paper›PMID 35949899›Full record

ArticleCase reports in oncology

Complete Spontaneous Regression of Squamous-Cell Lung Cancer: A Case Report.

Allan Klitgaard, Anders Løkke, Jakob Lager, Torben Riis Rasmussen, Ole Hilberg

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Spontaneous Regression in Pancreatic Neuroendocrine Tumor.Internal medicine (Tokyo, Japan) · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Allan KlitgaardDepartment of Regional Health Research, University of Southern Denmark, Odense, Denmark.
Anders LøkkeDepartment of Regional Health Research, University of Southern Denmark, Odense, Denmark.
Jakob LagerDepartment of Internal Medicine, The Regional Hospital in Horsens, Horsens, Denmark.
Torben Riis RasmussenDepartment of Respiratory Diseases and Allergy, Aarhus University Hospital, Aarhus, Denmark.
Ole HilbergDepartment of Regional Health Research, University of Southern Denmark, Odense, Denmark.
University of Southern Denmark · DKAarhus University Hospital · DKRegional Hospital Horsens · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spontaneous regression of cancer is an extremely rare phenomenon, and it has been described in only a few cases of pulmonary cancer. We report a case of complete spontaneous regression of squamous-cell lung cancer (SCLC) following a core needle biopsy in a 67-year-old female patient with two previous lung cancers and concomitant follicular lymphoma. The patient was diagnosed with SCLC after 4 core needle biopsies from a nodule in the left upper lobe and at the same time suspected of having follicular lymphoma. Treatment for the lung cancer was delayed by approximately 8 weeks because the diagnosis of lymphoma was both challenging and time-consuming. A computed tomography scan was performed in relation to the scheduled treatment for SCLC, showing that the pulmonary nodule had disappeared completely. Most other cases of spontaneous regression of lung cancer hint at the involvement of immunological factors, and this case possibly involves a combination of mechanical and local immunological factors. Genetic and immunological analysis of patients showing spontaneous regression of cancers could provide valuable information.

Indexed as

Computed tomographyCore needle biopsyFollicular lymphomaNon-small-cell lung cancerSpontaneous regression

Identifiers

PMID35949899
PMCPMC9251478
OpenAlexW4283080685

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.