Evidence map›Paper›PMID 35949866›Full record

ArticleArchives of rheumatology2022

Journey of rheumatoid arthritis patients in Tunisia: From symptoms to treatment.

Alia Fazaa, Hiba Bettaieb, Meriem Sellami, Saoussen Miladi, Kmar Ouenniche, Leila Souebni, Selma Kassab, Selma Chekili, Leith Zakraoui, Kaouther Abdelghani and 1 more

Abstract read
In one paragraph

Article in Archives of rheumatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alia FazaaDepartment of Rheumatology, Mongi Slim Hospital, La Marsa, Tunisia Faculté de Médecine de Tunis, Tunis El Manar University, Tunis, Tunisia.
Hiba BettaiebDepartment of Rheumatology, Mongi Slim Hospital, La Marsa, Tunisia Faculté de Médecine de Tunis, Tunis El Manar University, Tunis, Tunisia.
Meriem SellamiDepartment of Rheumatology, Mongi Slim Hospital, La Marsa, Tunisia Faculté de Médecine de Tunis, Tunis El Manar University, Tunis, Tunisia.
Saoussen MiladiDepartment of Rheumatology, Mongi Slim Hospital, La Marsa, Tunisia Faculté de Médecine de Tunis, Tunis El Manar University, Tunis, Tunisia.
Kmar OuennicheDepartment of Rheumatology, Mongi Slim Hospital, La Marsa, Tunisia Faculté de Médecine de Tunis, Tunis El Manar University, Tunis, Tunisia.
Leila SouebniDepartment of Rheumatology, Mongi Slim Hospital, La Marsa, Tunisia Faculté de Médecine de Tunis, Tunis El Manar University, Tunis, Tunisia.
Selma KassabDepartment of Rheumatology, Mongi Slim Hospital, La Marsa, Tunisia Faculté de Médecine de Tunis, Tunis El Manar University, Tunis, Tunisia.
Selma ChekiliDepartment of Rheumatology, Mongi Slim Hospital, La Marsa, Tunisia Faculté de Médecine de Tunis, Tunis El Manar University, Tunis, Tunisia.
Leith ZakraouiDepartment of Rheumatology, Mongi Slim Hospital, La Marsa, Tunisia Faculté de Médecine de Tunis, Tunis El Manar University, Tunis, Tunisia.
Kaouther AbdelghaniDepartment of Rheumatology, Mongi Slim Hospital, La Marsa, Tunisia Faculté de Médecine de Tunis, Tunis El Manar University, Tunis, Tunisia.
Ahmed LaatarDepartment of Rheumatology, Mongi Slim Hospital, La Marsa, Tunisia Faculté de Médecine de Tunis, Tunis El Manar University, Tunis, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aims to assess the different delays of rheumatoid arthritis (RA) patients' journey from disease onset to treatment initiation and to identify possible influencing factors. Patients and methods: This cross-sectional study included a total of 100 patients (14 males, 86 females; mean age: 56.5±12.4 years; range, 26 to 82 years) who met the 2010 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) criteria for RA between January 2019 and January 2020. Demographic and clinical data and disease characteristics were collected from the patient interviews and medical files. Five different intervals were defined from symptom onset until the initiation of conventional synthetic disease-modifying anti-rheumatic drugs (csDMARDs). Results: The mean age at RA onset was 46.6±12.4 years. Median delays from onset of symptoms until general practitioner (GP) and rheumatologist consultations were six (range, 0.25 to 240) months and 12 (range, 0 to 242) months, respectively. Median delays from onset of symptoms to RA diagnosis and treatment with csDMARDs were 15.7 (range, 2 to 252) months and 18 (range, 2 to 270) months, respectively. The mean number of consultations was 7.3±4.2 and the median number of physicians visited before the diagnosis was three (range, 1 to 8). The RA diagnosis delay was associated with rural geographic environment (p=0.02), lack of social insurance (p=0.027), progressive symptoms onset (p=0.006), morning stiffness (p=0.023), being initially examined by a GP (p=0.02), number of consultations (p<0.001; r=0.49), and number of physicians consulted before diagnosis (p=0.001; r=0.33) respectively. Based on the patients' self-perception, the main causes of this long delay were lack of financial means (33%), wait times until exploration results (31%), wait times until the first GP or rheumatologist visit (26%), and geographical difficulty in accessing healthcare services (18%). Conclusion: Our study results suggest that patients with RA experience a significant delay until diagnosis and initiation of treatment. Healthcare providers should urgently consider factors related to diagnosis delay to shorten RA patients' journey.

Indexed as

Diagnosis delaydisease managementrheumatoid arthritistherapeutics

Identifiers

PMID35949866
PMCPMC9326372

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.