ArticleWorld journal of clinical cases2022
Modified endoscopic ultrasound-guided selective N-butyl-2-cyanoacrylate injections for gastric variceal hemorrhage in left-sided portal hypertension: A case report.
Article in World journal of clinical cases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 6 citations in OpenAlex.
- Endoscopic ultrasound-guided perforator-targeted embolization for gastric variceal bleeding due to left-sided portal hypertension.Endoscopy · 2026Trial
- Treatment Strategy for Gastric Variceal Bleeding Caused by Sinistral Portal Hypertension Based on Hemodynamic Characteristics: A Case Report.Iranian journal of medical sciences · 2026Article
- Necessity and Reconstruction Methods of Splenic Vein After Resection of the Portomesenteric Junction During Resections for Pancreatic Cancer.Current oncology (Toronto, Ont.) · 2025Review
- Case report: Upper gastrointestinal bleeding associated with pancreatic segmental portal hypertension: six case reports and literature review.Frontiers in medicine · 2025Article
- Safety and efficacy of modified endoscopic ultrasound-guided selective N-butyl-2-cyanoacrylate injections for gastric variceal hemorrhage in left-sided portal hypertension.World journal of gastrointestinal endoscopy · 2024Article
- Endoscopic Ultrasound in Pancreatology: Focus on Inflammatory Diseases and Interventions.Visceral medicine · 2023Review
- Endoscopic ultrasound-guided diagnosis and treatment of gastric varices.World journal of gastrointestinal endoscopy · 2022Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLeft-sided portal hypertension (LSPH), also known as sinistral portal hypertension or regional portal hypertension, refers to extrahepatic portal hypertension caused by splenic vein obstruction or stenosis. N-butyl-2-cyanoacrylate (NBC) has been widely used in the endoscopic hemostasis of portal hypertension, but adverse events including renal or pulmonary thromboembolism, mucosal necrosis and gastrointestinal (GI) bleeding may occur after treatment. Herein, we report successfully managing gastric variceal (GV) hemorrhage secondary to LSPH using modified endoscopic ultrasound (EUS)-guided selective NBC injections. CASE SUMMARY: A 35-year-old man was referred to our hospital due to an upper GI hemorrhage. Gastroscopy revealed GV hemorrhage and computed tomography venography (CTV) confirmed LSPH. The patient requested endoscopic procedures and rejected surgical therapies including splenectomy. EUS-guided selective NBC injections were performed and confluences of gastric varices were selected as the injection sites to reduce the injection dose. The "sandwich" method using undiluted NBC and hypertonic glucose was applied. No complications occurred. The patient was followed up regularly after discharge. Three months later, the follow-up gastroscopy revealed firm gastric submucosa with no sign of NBC expulsion and the follow-up CTV showed improvements in LSPH. No recurrent GI hemorrhage was reported during this follow-up period.
conclusionEUS-guided selective NBC injection may represent an effective and economical treatment for GV hemorrhage in patients with LSPH.
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