Evidence map›Paper›PMID 35949789›Full record

ArticleCureus2022

Herpes Simplex Virus Type 1 (HSV-1) Meningoencephalitis in an Immunocompetent Young Adolescent Female.

Monica Garcia, Florentina Litra

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Monica GarciaPediatrics, University of Florida, Pensacola, USA.
Florentina LitraPediatrics, University of Florida, Pensacola, USA.
University of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The case that we report occurred in a previously healthy, fully immunized 13-year-old female presenting with severe unilateral headaches and generalized tonic-clonic seizures and subsequently diagnosed with herpes simplex virus type 1 (HSV-1) meningoencephalitis. The patient was successfully treated with acyclovir and seizures were controlled with valproic acid. The HSV meningoencephalitis has high morbidity and mortality. Our case highlights one of the severe presentations of HSV meningoencephalitis in young adolescents that can manifest with headaches, fever, seizures, focal neurologic signs, and altered mental status. We also highlight the need for a thorough workup among pediatric providers in the emergency and inpatient departments to avoid delays in diagnosis that can lead to poor outcomes.

Indexed as

acute encephalitisherpes simplex virus type 1hsv-1hsv meningitispediatric seizureviral meningitisviral meningoencephalitis

Identifiers

PMID35949789
PMCPMC9358060
OpenAlexW4284988007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.