Evidence map›Paper›PMID 35949642›Full record

ReviewReproductive medicine and biology

Fertility and sexual dysfunction in young male cancer survivors.

Yasushi Yumura, Teppei Takeshima, Mitsuru Komeya, Shinnosuke Kuroda, Tomoki Saito, Jurii Karibe

Open access · goldAbstract readReview
In one paragraph

Review in Reproductive medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Observational
  5. Review
  6. Review
  7. Immune Checkpoint Inhibitors Impact Fertility: A Review.Reviews on recent clinical trials · 2025
    Review
  8. Navigating an uncertain future: a qualitative study exploring thoughts about fertility and oncofertility counseling among young men with cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yasushi YumuraDepartment of Urology, Reproduction Center Yokohama City University, Medical Center Yokohama City Japan.ORCID https://orcid.org/0000-0003-0909-478X
Teppei TakeshimaDepartment of Urology, Reproduction Center Yokohama City University, Medical Center Yokohama City Japan.ORCID https://orcid.org/0000-0003-2733-5487
Mitsuru KomeyaDepartment of Urology, Reproduction Center Yokohama City University, Medical Center Yokohama City Japan.ORCID https://orcid.org/0000-0002-0744-7492
Shinnosuke KurodaDepartment of Urology, Reproduction Center Yokohama City University, Medical Center Yokohama City Japan.ORCID https://orcid.org/0000-0001-8890-0297
Tomoki SaitoDepartment of Urology, Reproduction Center Yokohama City University, Medical Center Yokohama City Japan.
Jurii KaribeDepartment of Urology, Reproduction Center Yokohama City University, Medical Center Yokohama City Japan.
Yokohama City University Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Newly emerging serious post-treatment complications among young male cancer survivors involve fertility and sexual function, preventing them from pursuing a normal family life. Methods: We studied and summarized published studies that assess the relationship between cancer treatments and reduced spermatogenesis or sexual dysfunction. Main findings: Infertility often occurs because of anticancer therapies that impair spermatogenesis. While some patients postremission functionally recover fertility, others experience a decreased sperm count and azoospermia. Fertility-preserving modalities are currently being promoted worldwide to preserve spermatogenesis following cancer therapy. Patients who can ejaculate and have sperm in their semen should cryopreserve semen. However, for patients who have never ejaculated before puberty or in whom spermatogenesis has not been established, testis biopsy is performed to collect and preserve sperm or germ cells. Fertility preservation is gaining popularity and requires continuous information dissemination to oncologists and cancer treatment professionals. Furthermore, male sexual dysfunction predominantly involves erectile dysfunction and ejaculation disorder. Conclusion: Although preventive and therapeutic methods for these disorders have been established within urology, patients and medical professionals in other fields remain uninformed of these advances. Therefore, dissemination of information regarding fertility preservation techniques should be accelerated.

Indexed as

chemotherapyejaculationerectile dysfunctionradiotherapyspermatogenesis

Identifiers

PMID35949642
PMCPMC9356720
OpenAlexW4290052941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.