Evidence map›Paper›PMID 35949557›Full record

ArticleClinical nutrition research2022

Anti-hypertensive Effects of Artichoke Supplementation in Adults: A Systematic Review and Dose-response Meta-analysis of Randomized Controlled Trials.

Mohammad Reza Amini, Fatemeh Sheikhhossein, Mohsen Alvani, Seyyed Morteza Seyyed Shoura, Asma Sohrabnavi, Ehsan Heidarian, Azita Hekmatdoost

Abstract read
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In one paragraph

Article in Clinical nutrition research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohammad Reza AminiStudent Research Committee, Department of Clinical Nutrition and Dietetics, Faculty of Nutrition Sciences and Food Technology, National Nutrition & Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran 198396-3113, Iran.ORCID https://orcid.org/0000-0003-0640-2142
Fatemeh SheikhhosseinDepartment of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Tehran 14155-6117, Iran.ORCID https://orcid.org/0000-0002-0076-361X
Mohsen AlvaniDepartment of Medicinal Chemistry, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, 81746-73461, Iran.ORCID https://orcid.org/0000-0002-2221-2704
Seyyed Morteza Seyyed ShouraStudent Research Committee, Tabriz University of Medical Sciences, Tabriz 5166614711, Iran.ORCID https://orcid.org/0000-0003-1931-1338
Asma SohrabnaviStudent Research Committee, Tabriz University of Medical Sciences, Tabriz 5166614711, Iran.ORCID https://orcid.org/0000-0002-5090-2673
Ehsan HeidarianDepartment of Anatomy, School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran 14155-6117, Iran.ORCID https://orcid.org/0000-0003-2119-6682
Azita HekmatdoostDepartment of Clinical Nutrition & Dietetics, National Nutrition & Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran 198396-3113, Iran.ORCID https://orcid.org/0000-0002-1944-0052

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite controversies, no earlier study has systematically summarized findings from earlier studies on the effect of artichoke supplementation on blood pressure. Therefore, current systematic review and meta-analysis was done on the effect of artichoke supplementation on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in adults. Five databases were searched from inception to January 2022 using relevant keywords. All randomized clinical trials investigating the impact of oral artichoke supplementation on any of the blood pressure parameters including SBP or/and DBP were included. Out of 1,507 citations, 7 trials that enrolled 472 subjects were included. Artichoke supplementation resulted in significant reduction in SBP (weighted mean difference [WMD], -2.01 mmHg; 95% confidence interval [CI], -3.78, -0.24; p = 0.026) and DBP (WMD, -1.45 mmHg; 95% CI, -2.81, -0.08; p = 0.038). Greater effects on SBP were detected in trials using ≤ 500 mg artichoke, lasted > 8 weeks, participants aged < 50 years' old and sample size ≤ 70. There was also a similar impact of artichoke on DBP. However, significant non-linear associations were found between artichoke supplementation dosage and study duration with both SBP (for dosage: p

Indexed as

ArtichokeBlood pressureHypertension

Identifiers

PMID35949557
PMCPMC9348915

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.