Evidence map›Paper›PMID 35949518›Full record

ArticleFujita medical journal2022

Establishment of the menthol test as a clinical evaluation method for oxaliplatin-induced neuropathy.

Yeongcheol Cheong, Hidetoshi Katsuno, Hiroshi Matsuoka, Masahiro Mizuno, Tomoyoshi Endo, Tadahiro Kamiya, Yosuke Tajima, Keigo Ashida, Yoshikazu Koide, Koji Masumori and 6 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Fujita medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Yeongcheol CheongDepartment of Gastroenterological Surgery, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan.
Hidetoshi KatsunoDepartment of Gastroenterological Surgery, Fujita Health University, School of Medicine, Okazaki, Aichi, Japan.
Hiroshi MatsuokaDepartment of Gastroenterological Surgery, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan.
Masahiro MizunoDepartment of Surgery, Ieda Hospital, Toyota, Aichi, Japan.
Tomoyoshi EndoDepartment of Gastroenterological Surgery, Fujita Health University, School of Medicine, Okazaki, Aichi, Japan.
Tadahiro KamiyaDepartment of Gastroenterological Surgery, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan.
Yosuke TajimaDepartment of Gastroenterological Surgery, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan.
Keigo AshidaDepartment of Surgery, Tottori Prefectural Central Hospital, Tottori ,Tottori, Japan.
Yoshikazu KoideDepartment of Gastroenterological Surgery, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan.
Koji MasumoriDepartment of Gastroenterological Surgery, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan.
Harunobu SatoDepartment of Gastroenterological Surgery, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan.
Tsunekazu HanaiDepartment of Advanced Robotic and Endoscopic Surgery, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan.
Kotaro MaedaInternational Medical Center, Fujita Health University Hospital, Toyoake, Aichi, Japan.
Ichiro UyamaDepartment of Advanced Robotic and Endoscopic Surgery, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan.
Junichiro HiroDepartment of Gastroenterological Surgery, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan.
Koichi SudaDepartment of Gastroenterological Surgery, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan.
Fujita Health University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To determine whether the tongue menthol test, which measures the cold sensation detection threshold (CDT) of the tongue, used before and after oxaliplatin administration is an objective evaluation method for oxaliplatin-induced peripheral neuropathy (OPN). Methods: The tongue menthol test was administered to patients both before and after undergoing chemotherapy containing oxaliplatin for colorectal cancer. The tongue menthol test was conducted by applying a menthol solution (a selective agonist of transient receptor potential cation channel subfamily M member 8 [TRPM8]) to the tongue and measuring the CDT. Results: The mean CDT before the first dose of oxaliplatin was 0.34% (0.005%-1%; Conclusions: By performing a menthol test in oxaliplatin-treated patients, it may be possible to objectively predict the exacerbation of peripheral neuropathy at an early stage.

Indexed as

MentholOPNOxaliplatinOxaliplatin-induced neuropathy

Identifiers

PMID35949518
PMCPMC9358673
OpenAlexW4291019141

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.