Evidence map›Paper›PMID 35949510›Full record

ArticleFASEB bioAdvances2022

Elevated serum Cripto-1 and VEGF levels in patients with non-small cell lung cancer.

Chunhua Xu, Jue Zou, Li Li, Qi Yuan, Wei Wang

Open access · goldAbstract read
In one paragraph

Article in FASEB bioAdvances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chunhua XuDepartment of Respiratory Medicine, Affiliated Nanjing Brain Hospital Nanjing Medical University Nanjing China.ORCID https://orcid.org/0000-0001-8728-2183
Jue ZouDepartment of Respiratory Medicine, Affiliated Nanjing Brain Hospital Nanjing Medical University Nanjing China.
Li LiDepartment of Respiratory Medicine, Affiliated Nanjing Brain Hospital Nanjing Medical University Nanjing China.
Qi YuanDepartment of Respiratory Medicine, Affiliated Nanjing Brain Hospital Nanjing Medical University Nanjing China.
Wei WangDepartment of Respiratory Medicine, Affiliated Nanjing Brain Hospital Nanjing Medical University Nanjing China.
Nanjing Brain Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cripto-1 (CR-1) facilitates vascular endothelial growth factor (VEGF) expression, and these markers are associated with various tumor cell proliferation, angiogenesis, and metastasis. The main aim of our study was to investigate the clinical value of CR-1 and VEGF for non-small cell lung cancer (NSCLC) patients. Serum samples were collected from 312 patients with NSCLC and 120 healthy controls. The levels of CR-1 and VEGF were measured by enzyme-linked immunosorbent assay (ELISA). The serum levels of CR-1 and VEGF in NSCLC patients were significantly higher than those of healthy controls (

Indexed as

biomarkerCripto‐1NSCLCsurvivalVEGF

Identifiers

PMID35949510
PMCPMC9353448
OpenAlexW4223590156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.