Evidence map›Paper›PMID 35949401›Full record

ArticleOpen forum infectious diseases2022

Care Navigation Increases Initiation of Hepatitis C Treatment After Release From Prison in a Prospective Randomized Controlled Trial: The C-LINK Study.

Timothy Papaluca, Anne Craigie, Lucy McDonald, Amy Edwards, Rebecca Winter, Annabelle Hoang, Alex Pappas, Aoife Waldron, Kelsey McCoy, Mark Stoove and 7 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Timothy PapalucaDepartment of Gastroenterology, St Vincent's Hospital, Melbourne, Victoria, Australia.
Anne CraigieDepartment of Gastroenterology, St Vincent's Hospital, Melbourne, Victoria, Australia.
Lucy McDonaldDepartment of Gastroenterology, St Vincent's Hospital, Melbourne, Victoria, Australia.
Amy EdwardsDepartment of Gastroenterology, St Vincent's Hospital, Melbourne, Victoria, Australia.
Rebecca WinterDepartment of Gastroenterology, St Vincent's Hospital, Melbourne, Victoria, Australia.
Annabelle HoangDepartment of Gastroenterology, St Vincent's Hospital, Melbourne, Victoria, Australia.
Alex PappasDepartment of Gastroenterology, St Vincent's Hospital, Melbourne, Victoria, Australia.
Aoife WaldronDepartment of Gastroenterology, St Vincent's Hospital, Melbourne, Victoria, Australia.
Kelsey McCoyDepartment of Gastroenterology, St Vincent's Hospital, Melbourne, Victoria, Australia.
Mark StooveBurnet Institute, The University of Melbourne, Melbourne, Victoria, Australia.
Joseph DoyleBurnet Institute, The University of Melbourne, Melbourne, Victoria, Australia.
Margaret HellardBurnet Institute, The University of Melbourne, Melbourne, Victoria, Australia.
Jacinta HolmesDepartment of Gastroenterology, St Vincent's Hospital, Melbourne, Victoria, Australia.
Michael MacIsaacDepartment of Gastroenterology, St Vincent's Hospital, Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0001-9391-1468
Paul DesmondDepartment of Gastroenterology, St Vincent's Hospital, Melbourne, Victoria, Australia.
David IserDepartment of Gastroenterology, St Vincent's Hospital, Melbourne, Victoria, Australia.
Alexander J ThompsonDepartment of Gastroenterology, St Vincent's Hospital, Melbourne, Victoria, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Prison-based hepatitis C treatment is safe and effective; however, many individuals are released untreated due to time or resource constraints. On community re-entry, individuals face a number of immediate competing priorities, and in this context, linkage to hepatitis C care is low. Interventions targeted at improving healthcare continuity after prison release have yielded positive outcomes for other health diagnoses; however, data regarding hepatitis C transitional care are limited. Methods: We conducted a prospective randomized controlled trial comparing a hepatitis C care navigator intervention with standard of care for individuals released from prison with untreated hepatitis C infection. The primary outcome was prescription of hepatitis C direct-acting antivirals (DAA) within 6 months of release. Results: Forty-six participants were randomized. The median age was 36 years and 59% were male. Ninety percent ( Conclusions: Care navigation increased hepatitis C treatment uptake among untreated individuals released from prison. Public policy should support similar models of care to promote treatment in this high-risk population. Such an approach will help achieve hepatitis C elimination as a public health threat.

Indexed as

DAAeliminationhepatitis Cprisontransitional care

Identifiers

PMID35949401
PMCPMC9356682

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.