Evidence map›Paper›PMID 35949301›Full record

ArticleIranian journal of basic medical sciences2022

Tetratricopeptide repeat domain 9A knockout induces social anxiety and impairs offense behaviors in female mice.

Wing Shan Yu, Li Guan, Shawn Zheng Kai Tan, Smeeta Shrestha, Yu Zuan Or, Thomas Lufkin, Valerie Cl Lin, Lee Wei Lim

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Iranian journal of basic medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Wing Shan YuNeuromodulation Laboratory, School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, P.R. China.
Li GuanNeuromodulation Laboratory, School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, P.R. China.
Shawn Zheng Kai TanNeuromodulation Laboratory, School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, P.R. China.
Smeeta ShresthaSchool of Biological Sciences, Nanyang Technological University, 50 Nanyang Avenue, Singapore.
Yu Zuan OrSchool of Biological Sciences, Nanyang Technological University, 50 Nanyang Avenue, Singapore.
Thomas LufkinDepartment of Biology, Clarkson University, Potsdam, New York, United States.
Valerie Cl LinSchool of Biological Sciences, Nanyang Technological University, 50 Nanyang Avenue, Singapore.
Lee Wei LimNeuromodulation Laboratory, School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, P.R. China.
University of Hong Kong · HKNanyang Technological University · SGClarkson University · USDr. Hari Singh Gour University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The involvement of tetratricopeptide repeat domain 9A (TTC9A) in anxiety-like behaviors through estrogen action has been reported in female mice, this study further investigated its effects on social anxiety and aggressive behaviors. Materials and sMethods: Using female Ttc9a knockout ( Results: We observed significant social behavioral deficits with pronounced social and non-social anxiogenic phenotypes in female Conclusion: Future study investigating mechanisms underlying the social anxiety-like behavioral changes in

Indexed as

AggressionAnxietyBehavioral testsSocial behaviorTetratricopeptide repeat - domain 9A (TTC9A)

Identifiers

PMID35949301
PMCPMC9320210
OpenAlexW4291020164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.