Evidence map›Paper›PMID 35949229›Full record

ArticleCase reports in gastroenterology

Acute Chest Pain as an Infusion Reaction to Vedolizumab.

Asaf Levartovsky, Miri Yavzori, Ella Fudim, Uri Kopylov, Shomron Ben-Horin, Bella Ungar

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Asaf LevartovskyDepartment of Gastroenterology, Sheba Medical Center Tel Hashomer, Tel Aviv University, Tel-Aviv, Israel.
Miri YavzoriDepartment of Gastroenterology, Sheba Medical Center Tel Hashomer, Tel Aviv University, Tel-Aviv, Israel.
Ella FudimDepartment of Gastroenterology, Sheba Medical Center Tel Hashomer, Tel Aviv University, Tel-Aviv, Israel.
Uri KopylovDepartment of Gastroenterology, Sheba Medical Center Tel Hashomer, Tel Aviv University, Tel-Aviv, Israel.
Shomron Ben-HorinDepartment of Gastroenterology, Sheba Medical Center Tel Hashomer, Tel Aviv University, Tel-Aviv, Israel.
Bella UngarDepartment of Gastroenterology, Sheba Medical Center Tel Hashomer, Tel Aviv University, Tel-Aviv, Israel.
Tel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vedolizumab-associated adverse effects, including infusion reactions, are generally uncommon. Less than 5% of patients experience an infusion-related reaction. We report a 67-year-old male with ulcerative colitis under prolonged maintenance therapy who presented with recurring chest pain occurring immediately after consecutive vedolizumab infusions. Medical workup of possible etiologies for chest pain were investigated and excluded. Vedolizumab drug trough levels were negative, accompanied by high detectable levels of anti-vedolizumab antibodies. These findings demonstrate an uncommon case of an infusion reaction to vedolizumab infusion.

Indexed as

Adverse reactionChest painVedolizumab

Identifiers

PMID35949229
PMCPMC9294963
OpenAlexW4283703355

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.