Evidence map›Paper›PMID 35949220›Full record

ArticleWorld journal of gastrointestinal oncology2022

Characterizing the patient experience during neoadjuvant therapy for pancreatic ductal adenocarcinoma: A qualitative study.

Lena Stevens, Zachary J Brown, Ryan Zeh, Christina Monsour, Sharla Wells-Di Gregorio, Heena Santry, Aslam M Ejaz, Timothy Michael Pawlik, Jordan M Cloyd

Open access · diamondAbstract read
In one paragraph

Article in World journal of gastrointestinal oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Factors impacting informed decision-making for patients with pancreatic cancer: a qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Lena StevensDepartment of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, United States.
Zachary J BrownDepartment of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, United States.
Ryan ZehDepartment of General Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, United States.
Christina MonsourDepartment of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, United States.
Sharla Wells-Di GregorioDepartment of Psychiatry, Center for Palliative Care, The Ohio State University Wexner Medical Center, Columbus, OH 43210, United States.
Heena SantryDepartment of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, United States.
Aslam M EjazDepartment of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, United States.
Timothy Michael PawlikDepartment of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, United States.
Jordan M CloydDepartment of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, United States. jordan.cloyd@osumc.edu.
The Ohio State University Wexner Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeoadjuvant therapy (NT) has increasingly been utilized for patients with localized pancreatic ductal adenocarcinoma (PDAC). It is the recommended approach for borderline resectable (BR) and locally advanced (LA) cancers and an increasingly utilized option for potentially resectable (PR) disease. Despite its increased use, little research has focused on patient-centered metrics among patients undergoing NT, including patient experiences, preferences, and recommendations. A better understanding of all aspects of the patient experience during NT may identify opportunities to design interventions aimed at improving quality of life; it may also facilitate the completion of NT and receipt of surgery, ultimately optimizing long-term outcomes.

aimTo understand the experience of patients initiating and receiving NT to identify opportunities to improve neoadjuvant cancer care delivery.

methodsSemi-structured interviews of patients with localized PDAC during NT were conducted to explore their experience initiating and receiving NT. Interviews took place between August 2020 and October 2021. Due to the descriptive nature of the research, questions were open ended. Interviews were conducted over the phone, audio recorded and then transcribed. All interviews were coded by two independent researchers using NVivo 12, iteratively identifying themes until thematic saturation was achieved. An integrative approach to qualitative analysis was used, utilizing both inductive and deductive methods.

resultsA total of 12 patients with localized PDAC were interviewed. Patients with BR (

conclusionThis study provides a framework to allow for a better understanding of the PDAC patient experience during NT and highlights opportunities to improve quality and quantity of life outcomes.

Indexed as

Neoadjuvant therapyPancreatic ductal adenocarcinomaPatient-centered carePatient experienceQualitative researchQuality of life

Identifiers

PMID35949220
PMCPMC9244990
OpenAlexW4281819995

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.