Evidence map›Paper›PMID 35948955›Full record

Observational studyBMC ophthalmology2022

Evaluation of macular microvascular density using optical coherence tomography angiography in patients with Posner-Schlossman syndrome.

Xiu-Juan Guo, Di Chen, Li-Jun Zhou, Shu-Ke Luo, Yan Lu, Jing-Jing Guo

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Observational
  2. Cytomegalovirus-positive Posner-Schlossman syndrome: to compare differences in retinal vessel area density between the affected and non-affected eye using optical coherence tomography angiography.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Observational
  3. Article
  4. The impact of intraocular pressure on optical coherence tomography angiography: A review of current evidence.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xiu-Juan GuoDepartment of Ophthalmology, Affiliated Foshan Hospital, Southern Medical University, Foshan, 528000, People's Republic of China. guo_xiujuan@126.com.
Di ChenDepartment of Ophthalmology, Affiliated Foshan Hospital, Southern Medical University, Foshan, 528000, People's Republic of China.
Li-Jun ZhouState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Centre, Sun Yat-Sen University, Guangzhou, 510000, People's Republic of China.
Shu-Ke LuoDepartment of Ophthalmology, Affiliated Foshan Hospital, Southern Medical University, Foshan, 528000, People's Republic of China.
Yan LuDepartment of Ophthalmology, Affiliated Foshan Hospital, Southern Medical University, Foshan, 528000, People's Republic of China.
Jing-Jing GuoDepartment of Ophthalmology, Affiliated Foshan Hospital, Southern Medical University, Foshan, 528000, People's Republic of China.
Southern Medical University · CNSun Yat-sen University · CN

Funding

Science and Technology Planning Project of Foshan City 1920001001332
6 · The paper itself

Abstract

backgroundOptical coherence tomography angiography (OCTA) is a novel technology that provides a noninvasive, dye-less method to visualize the blood vessels of the retina. In the present study, we investigate macular microvascular density and the correlation of ocular and demographic factors using OCTA in Posner-Schlossman syndrome (PSS) patients.

methodsThis is a prospective observational study. All PSS patients and age- and sex-matched healthy subjects underwent complete ophthalmologic examination, and RE, BCVA, IOP, CCT, AL, CMT, GCIPI, RNFL, C/D ratio were recorded. The whole-image vessel density (wiVD) and whole-image perfusion density (wiPD), three-circle (1 mm central ring, 3 mm inner ring, 6 mm outer ring), and four-quadrant segmental VD and PD were calculated.

resultsSeventeen PSS patients and 17 healthy subjects were enrolled in this study. The mean age was 42.65 ± 11.22 years in PSS patients and 42.71 ± 10.50 years in healthy controls. IOP, CCT, and C/D ratio were higher in PSS-attacked eyes, and BCVA, OPP and RNFL thickness was lower than those in the fellow eyes (p < 0.05). BCVA and OPP were improved in the PSS-attacked eyes in intermittent period (p < 0.05). The wiVD and wiPD were lower in the PSS-affected eyes than in the fellow eyes and in the control eyes in the PSS-attacked period (p < 0.05). All segmental VD and PD was lower in the PSS affected eyes than in the healthy control eyes (p < 0.05). In intermittent period, the wiVD and wiPD were lower in the PSS-affected eyes than in the fellow eyes (p < 0.05). Age, CCT, and SSI were associated with macular wiVD and wiPD in PSS attacked period. Age and CCT were associated with macular wiVD and wiPD in PSS intermittent period.

conclusionDecreased macular superficial VD and PD was found in patients with Posner-Schlossman syndrome in attacked period and in remission. Macular wiVD and wiPD were associated with age, CCT and SSI in PSS patients.

Indexed as

Glaucoma, Open-AngleOptic DiskAdultFluorescein AngiographyHumansIntraocular PressureMicrovascular DensityMiddle AgedNerve FibersRetinal Ganglion CellsRetinal VesselsTomography, Optical CoherenceVisual FieldsVisual Field TestsCentral cornea thicknessIntraocular pressureMacular superficial vessel densityOcular perfusion pressureOptical coherence tomography angiographyPosner-Schlossman syndrome

Identifiers

PMID35948955
PMCPMC9364523
OpenAlexW4291396361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.